Transcriptomics is one of the flourishing “Omics” technologies (proteomics, genomics, metabolomics and others) across the globe. Transcriptomics research provides insights on structure and function of complete set of RNA molecules present in a given cell. Currently, the analysis of transcriptome of several organisms is facilitated with the help of advanced technological platforms such as next generation sequencing platforms followed by polymerase chain reaction, microarrays and gene regulation technologies. These technologies are applied in the process of drug discovery, medical research, clinical diagnosis of diseases and others. With the burgeoning demand for targeted therapeutics and continuous improvements in healthcare infrastructure, transcriptomics technologies promise lucrative commercialization prospects. Hence, transcriptomics research enables development of potential and novel therapeutics and diagnostics
Evolution of technological analysis platforms such as next generation sequencing technologies, microRNA technology, RNA interference technology and PCR technologies enable effective analysis of transcriptome of different organisms with greater precision and accuracy. Currently, there is a demand for technology sophistication to ensure optimum results. For example, presently, there is a need for multiplexed RNA sequencing and quantagene RT-PCR which enable the sequencing and analysis of numerous transcripts and reads simultaneously. These technological sophistications in turn create a demand for effective data analysis tools and service (bioinformatics) in order to handle and manage huge amount of data from these technological platforms
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Transcriptomics technologies are applied majorly in studying gene expression patterns, drug discovery and clinical diagnosis of disorders such as cardiovascular, central nervous system disorders, cancers and others. Transcriptome analysis tools and services are used in identification of novel gene sequences and potential drug targets. Also, they provide insights about gene expression patterns and gene regulation mechanisms that are responsible to trigger the functioning and production of proteins. There is a lot of complexity involved in study of structural and functional aspects of complete set of transcripts present in a given cell or population of cells. Henceforth, several pharmaceutical and biotechnology companies are investing in medical research to develop robust methodologies with high efficiency and reliability.
Geographically, North America dominated the global transcriptomics technologies market in 2012 with a revenue share of over 35%. Presence of well equipped medical and research laboratories, increased awareness of biotechnological research and increased participation of respective governments are some of the major factors responsible for region’s leadership position. Factors such as continuous improvisation in healthcare infrastructure, rigorous research and development initiatives followed by increased commercialization of research outcomes are expected to drive the growth of this market during the forecast period. In Asia-Pacific region ongoing development of technologies and infrastructure facilities along with increasing acceptance towards the novel approaches in biotechnology research will further enhance the uptake of transcriptomics technologies and drive market growth. On the other hand factors which might hamper the growth of overall transcriptomics market are lack of effective computational biology tools and services required for efficient analysis of complex data followed by lack of domain expertise.
