2024-03-17

A question was ask – are there significant gender differences with ME/CFS. A partial answer is possible from our citizen science data (Available here). The number of bacteria identify as statistical drops because we are reducing sample sizes. The table below shows the shifts that are seen in common with P < 0.01.

For Symptom of ME/CFS

ME/CFS With IBS

We find differences here.

ME/CFS Without IBS

We found no differences yet (given the sample size)

Irritable Bowel Syndrome

Following up from above and noting that there is a gender bias in incidence, we find some differences

Depression

Another condition with a gender association

Symptom: Problems remembering things

This is one of the characteristics of ME/CFS, Long Covid, etc

Symptom: Worsening of symptoms with stress.

Another common symptom of ME/CFS

Other Symptoms with Significant Gender Differences in patterns

Immune Manifestations: Abdominal Pain

Sleep: Unrefreshed sleep

Comorbid: High Anxiety

General: Fatigue

Neurological-Audio: hypersensitivity to noise

DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired

DePaul University Fatigue Questionnaire : Fatigue

Neurocognitive: Brain Fog

Neurocognitive: Problems remembering things

DePaul University Fatigue Questionnaire : Anxiety/tension

General: Myalgia (pain)

Immune Manifestations: Constipation

Post-exertional malaise: Rapid muscular fatigability,

Neuroendocrine Manifestations: Poor gut motility

Comorbid: Restless Leg

Comorbid: Small intestinal bacterial overgrowth (SIBO)

DePaul University Fatigue Questionnaire : Difficulty finding the right word

DePaul University Fatigue Questionnaire : Mood swings

DePaul University Fatigue Questionnaire : Pain in Multiple Joints without Swelling or Redness

Sleep: Problems falling asleep

Sleep: Problems staying asleep

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