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On the FDA, Drug Approvals, and Not Knowing Enough
via blogs.sciencemag

It doesn’t seem to have generated many headlines, but the FDA recently released a report (PDF) on the pace of drug development. Titled “Targeted Drug Development: Why Are Many Diseases Lagging Behind”, it seems to be motivated, at least in part, by a...
The EDGE: Phys.org Newsletter Wednesday, Apr 16
via findallpills

Explore MEMS applications in your circle of expertise with this online dependence from COMSOL Multiphysics. Learn from diligence leaders in this collection of video tutorials, user stories, pretence examples, and more. Check out the MEMS Showcase in...
BioGPS Spotlight on HumanMine
via sulab

In our last spotlight we covered FlyMine, one of two mines maintained by the InterMine group at Cambridge University. This week’s spotlight is on HumanMine, the second of the two aforementioned mines. Yo Yehudi (developer), and Rachel Lyne (biologist...
In Oxytocin We Trust
via neurocritic.blogspot

Oh oxytocin, you cuddly hug drug, you fine upstanding moral molecule, why are you so maligned by critics? That's because you're overrated, and misunderstood by those who look to you as a beacon of empathy, trust, love, peace, and prosperity. Sure, you...
Blog Post: Mice show the way: New insight into Mendelian (single-gene) disease
via community.jax

Mendelian diseases are diseases caused by a mutation in a single gene that arise spontaneously in the population. There are more than 4,500 known Mendelian diseases, and, according to the World Health Organization (WHO), the worldwide incidence of single...

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Statin Pathway (Homo sapiens) 1 Description Statins inhibit endogenous cholesterol production by competitive inhibition of HMG-CoA reductase (HMGCR), the enzyme that catalyzes conversion of HMG-CoA...

EGF/EGFR Signaling Pathway (Homo sapiens) - WikiPathways

EGF/EGFR Signaling Pathway (Homo sapiens) From WikiPathways SHC1 PIP2 CY Leads to through unknown mechanism Negative regulation of gene expression Translocation Description Epidermal growth factor...