For decades, the medical, electronics, military, automotive and aerospace industries have used conformal coatings for a variety of reasons, including to protect components from their environment, enhance lubricity, provide thermal and electrical insulation, stabilize delicate structures, and function as an interface that is biocompatible. As advances in technology demand devices and components become smaller in size, more complex in nature and face increasingly harsh environments, newer designs present challenges for many conformal coatings. Poly(para-xylylene), known as Parylene, is an ultra-thin, pinhole-free, inert, transparent conformal coating that meets these challenges. With a successful track record spanning more than 40 years, Parylene coatings have enhanced the reliability of numerous devices and components such as circuit boards, MEMS, LEDs, stents, pacemakers, electrosurgical tools, sensors, and elastomeric components, to name only a few.