2015-12-09

LONDON, Dec. 9, 2015 /PRNewswire/ -- This report analyzes the worldwide markets for Biophotonics in US$ Million by the following End-Use Sectors: Medical (Therapeutics, Diagnostics, & Others), and Non-Medical. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2014 through 2020. Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 85 companies including many key and niche players such as -

AdvanDx, Inc.
Affymetrix, Inc.
Andor Technology plc
Becton, Dickinson and Company
BioTek Instruments, Inc.

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I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations I-1 Disclaimers.............. I-2 Data Interpretation & Reporting Level I-2 Quantitative Techniques & Analytics I-3 Product Definitions and Scope of Study I-3 Medical Therapeutics..............I-3 Medical Diagnostics..............I-3 Others.............. I-3 Non-Medical.............. I-3

II. EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW.............. II-1 Prelude.............. II-1 Expanding Application Base as the Major Growth Driver II-2 Current and Future Analysis..............II-3 Competitive Landscape - Expanding Applications Attract New Players.............. II-4

2. MARKET TRENDS, ISSUES AND DRIVERS II-6 Optical In-Vitro Diagnostics - The Largest Market Segment for Biophotonics.............. II-6 Increasing Penetration of Diabetes Mellitus - Offers Opportunities for Biophotonics II-6 Global Diabetic Statistics - Opportunity Indicators II-7 Table 1: Worldwide Prevalence of Diabetes Mellitus by Region (2014 & 2035P) (includes corresponding Graph/Chart) II-7

Table 2: Ten Countries with the Highest DM Cases (2014) (includes corresponding Graph/Chart) II-8 Endoscopy - A Market with Immense Scope II-8 Ophthalmology and Dermatology Major Application Segments for Medical Lasers.............. II-8 Food Diagnostics - An Emerging Niche II-9 Drug Discovery & Development - A Potential Application Segment for Biophotonics.............. II-9 Opportunities Galore for Biophotonic Technologies in Infection Control.............. II-9 High-end Biophotonics to Find Major Application in Neurosciences II-10 Coherent Develops Genetically Encoded Ultrafast Fiber Laser for Application in Neuroscience II-11 Improving Healthcare Expenditure to Drive Demand for Biophotonics II-11 Table 3: Per-Capita Healthcare Expenditure in Select Regions (2014) (includes corresponding Graph/Chart) II-13

Table 4: Healthcare Spending as a Percentage of GDP by Geographic Region (2015E) (includes corresponding Graph/Chart).............. II-14 Ageing Population to Spruce Up Biophotonics Development II-14 Demographic Statistics - Opportunity Indicators for Biophotonics Market:..............II-16 Table 5: Global Population Statistics for the 65+ Age Group (2013) (includes corresponding Graph/Chart) II-16

Table 6: Elderly Population (60+ Years) as a Percentage of the Total Population (2012 & 2050) (includes corresponding Graph/Chart).............. II-17 Growing Prominence of Biophotonics in Cancer Detection II-17 Cancer Incidence and Mortality Statistics - A Perspective of Market Potential.............. II-18 Table 7: Worldwide Incidence of Cancer (2012, 2020 & 2030): Number of New Cases Diagnosed (includes corresponding Graph/Chart).............. II-18

Table 8: World Cancer Incidence by Geographic Region and Gender (2012): Number of New Cancer Cases Reported (in Thousands) for Asia-Oceania, Europe, North America, Latin America & the Caribbean, and Africa (includes corresponding Graph/Chart).............. II-18

Table 9: Global Cancer Incidence by Income Group: 2012 (in Thousands) (includes corresponding Graph/Chart) II-19

Table 10: World Cancer Mortality by Geographic Region and Gender (2012): Number of Cancer-Related Deaths (in Thousands) for Asia-Oceania, Europe, North America, Latin America & Caribbean, and Africa (includes corresponding Graph/Chart) II-19

Table 11: Global Incidence of Common Cancers in Men (2012): Number of New Cases Reported in Thousands for Lung & Bronchus, Prostate, Colorectal and Liver Cancers (includes corresponding Graph/Chart)..............II-20

Table 12: Global Incidence of Common Cancers in Women (2012): Number of New Cases Reported in Thousands for Breast, Colorectal, Lung & Bronchus and Liver Cancers (includes corresponding Graph/Chart)..............II-20 Cancer Prone Sites based on Age II-20 Biophotonics-based Tests for Detecting Coronary Artery Diseases II-21 Photonics-based Breath Analysis Gaining Traction II-21 OMI to Revolutionize Methodologies for Diagnosing and Treating Diseases.............. II-21 Advancements in Optical Filter Technology to Revolutionize Wearable Electronics and PoC Diagnostics II-22 Diagnostic & Therapeutic Applications of Biophotonics Attract R&D Funding.............. II-24 Private Foundations Come Forth to Invest in Biophotonics II-24 Notable Technology Innovations and Research Advancements in the Biophotonics Field..............II-25 CBSS Develops Optical Microscopes for Disease Diagnosis & Treatment.............. II-25 University of Adelaide Focuses on Biophotonics for Research on Life Processes.............. II-25 Texas A&M University's Invests in Multidisciplinary Biophotonics Research..............II-26 NSF Grants Funds for Biomolecule Imaging using X-Ray Lasers II-26 Photoplethysmography-Based DistancePPG to Aid in Monitoring Vital Signs.............. II-26 Permanent Fluorescent Label Helps Researchers in Studying Neural Activities.............. II-26 Researchers Develop Glucolight System for Non- Invasive Measurement of Blood Glucose Levels II-27 Researchers Develop SCAPE Microscopy for 3D Imaging of Moving Samples.............. II-27 Japanese Researchers Develop Nanolaser to Identify Specific Biomolecules.............. II-28 Novel Phototherapy and Imaging Technique to Target and Destroy Cancer Cells..............II-28 Researchers Develop Multicolor RGB Marking to Color-Code Neural Cells.............. II-29 EHT Model Holds Potential to Enable Tailored Optogenetics Proteins.............. II-29 Researchers at University of Buffalo to Develop Endoscope for High-Contrast Imaging of Cancer Tumors II-29 Photoacoustic Imaging to Provide Effective Solution to Detect Cervical Cancer.............. II-30 Photoacoustic Device Allows Researchers to Diagnose Melanoma II-30 LIAFS/DRS Technique to Improve Melanoma Diagnosis II-30 Raman Spectroscopy Enables Faster, Accurate Diagnosis of Cancer II-31 Light-based Approaches to Help Researchers in Studying Brain Function.............. II-31 Researchers Develop Lens-Free On-Chip Microscope to Produce High-Resolution Images..............II-32 Fluorescent Dye-Coated Nanoparticles to Target Disease Causing Genes.............. II-32 UK Sets Up Quantum Technology Research Hubs to Explore Light Detectors.............. II-32 Stimulation of Receptors Using Light to Relax Blood Vessels II-33 MIR Laser Produces X-Ray Pulses with High Flux II-33 Phosphorescent Bandage to Monitor Oxygen Concentration for Wound Assessment..............II-33 Sophisticated Microscopy Technique to Enable Single- Cell, High-Resolution Imaging of Entire Body II-34 Violet-Blue Light Controlled Medicine to Provide Effective Treatment Option for Diabetic Patients II-35 Magnetic Nanoparticles to Assist Researchers in Bio-Imaging Applications.............. II-35 UV Light with Manual Cleaning to Prevent Spread of Superbugs in Hospitals.............. II-36 Researchers Explore Use of OCT to Understand Acne Lesion II-36 Novel Fluorescent Probes to Enable Detection of Lysosomal pH Levels.............. II-36 Researchers Develop New Range of Fluorescence Markers for Imaging Applications..............II-37 Researchers Develop Optogenetic Technique to Map Neural Networks II-37 IR Quantum Cascade Laser to Provide Convenient Solution to Monitor Blood Glucose Levels II-38 Wearable Optical Device to Enable Timely Identification of Diabetes Complication..............II-38 New Fluorescence-enhanced Test to Identify People at Higher Risk of Developing Diabetes..............II-39 Fluorescence Imaging Techniques to Detect Alzheimer's Indicators in Eye.............. II-39 Adaptive Optics Allows Physicians to Detect Early Signs of Diabetes Eye Damage..............II-39 New Technique Uses Femtosecond Lasers for Controlled, Precise Drug Delivery.............. II-40

3. AN INTRODUCTION TO BIOPHOTONICS II-41 Definition.............. II-41 Select Light Sources for Biophotonics II-41 Gas Lasers.............. II-41 Diode Lasers.............. II-42 Applications.............. II-42 Biophotonics in Diagnostics..............II-42 Biophotonics in Therapeutics..............II-42 Biophotonics in Biotechnology II-43 Other Emerging Applications of Biophotonics II-43 Optical Sectional Microscopy II-43 Photon Limited Microscopy..............II-43 Fluorescence Microscopy..............II-43 Time-Resolved Fluorescence Spectroscopy II-43 Fluorescence Lifetime Imaging Microscopy II-44 Caged Bioactive Probes..............II-44 End-Use Sectors.............. II-44

4. PRODUCT INNOVATIONS/INTRODUCTIONS II-45 Taiwan Biophotonic Unveils DOE Reflective Sensor for Fingerless Wrist-Worn Pulse Oximeters II-45 Lumenis Introduces New ResurFX System for Skin Resurfacing Treatment.............. II-45 Olympus Introduces Two New Configurations to its FLUOVIEW FVMPE-RS Series.............. II-45 KLOX Technologies Obtains CE Mark for LumiHeal™ Medical Device II-45 AdvanDx Obtains FDA Approval for mecA XpressFISH™ II-45 BIOLASE Unveils EPIC™ X Diode Laser II-45 BioTek Unveils New Cytation Imaging Multi-Mode Reader II-46 Lumenis to Launch LightSheer® DESIRE™ and LightSheer® INFINITY™ in Europe..............II-46 Lumenis Unveils New Q-Switched Nd:YAG Module for the M22™ Platform.............. II-46 Lumenis Launches LightSheer® DESIRE™ and LightSheer® INFINITY™ Laser Hair Removal Systems..............II-46 Picoquant Unveils Picosecond Pulsed Diode Laser Head II-46 Biophotas Launches Celluma™ ELITE for Aesthetic Physician Market II-46 AdvanDx Introduces Candida QuickFISH Rapid Diagnostic II-46 AdvanDx Introduces Gram-Negative QuickFISH BC II-47 AdvanDx Launches Enterococcus QuickFISH BC II-47 BIOLASE Receives License to Sell EPIC 10 Soft-Tissue Diode Laser in Canada.............. II-47 Lumenis to Introduce ResurFX™..............II-47

5. RECENT INDUSTRY ACTIVITY..............II-48 Newport Corporation to Acquire FEMTOLASERS II-48 Hamilton Thorne Takes Over CRi's Reproductive Imaging Product Range.............. II-48 The University of St Andrews Enters into Partnership with M Squared Lasers.............. II-48 Edmund Optics Enters into Partnership with Luxexcel Group II-48 First Light Imaging Obtains EC Grant for Working on IR Camera II-48 Excelitas Technologies Collaborates with Kinetic River Corp to Design Flow Cytometer Prototype II-48 Horiba Acquires Photon Technology International II-48 Newport Takes Over V-Gen..............II-49 Zecotek Signs Joint Collaboration Agreement with Hamamatsu Photonics.............. II-49 Bausch + Lomb to Take Over Technolas Perfect Vision GmbH II-49

6. FOCUS ON SELECT GLOBAL PLAYERS..............II-50 AdvanDx, Inc. (US)..............II-50 Affymetrix, Inc. (US)..............II-50 Andor Technology plc (Ireland) II-50 Becton, Dickinson and Company (US) II-51 BioTek Instruments, Inc. (US)..............II-51 BIOLASE, Inc. (US)..............II-51 Carl Zeiss MicroImaging GmbH (Germany) II-52 CEA-Leti (France).............. II-52 Endra, Inc. (US).............. II-52 Epi-Light Limited (Ireland)..............II-53 FEI Company (US).............. II-53 Glenbrook Technologies, Inc. (US) II-54 Hamamatsu Photonics K.K. (Japan) II-54 HORIBA, Ltd. (Japan)..............II-54 Lumenis Ltd. (Israel)..............II-55 Newport Corporation (US)..............II-55 Ocean Optics, Inc. (US)..............II-55 Olympus America, Inc. (US)..............II-56 PerkinElmer, Inc. (US)..............II-56 Photocure ASA (Norway)..............II-56 PicoQuant GmbH (Germany)..............II-57 Solta Medical, Inc. (US)..............II-57 Zecotek Photonics, Inc. (Singapore) II-57 Zenalux Biomedical, Inc. (US)..............II-58

7. GLOBAL MARKET PERSPECTIVE..............II-59 Table 13: World Recent Past, Current and Future Analysis for Biophotonics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............II-59

Table 14: World Historic Review for Biophotonics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) II-60

Table 15: World 14-Year Perspective for Biophotonics by Geographic Region - Percentage Breakdown of Revenues for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) II-61 Biophotonics Market Analytics by End-Use Sector II-62 Table 16: World Recent Past, Current and Future Analysis for Medical Applications of Biophotonics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-62

Table 17: World Historic Review for Medical Applications of Biophotonics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............II-63

Table 18: World 14-Year Perspective for Medical Applications of Biophotonics by Geographic Region - Percentage Breakdown of Revenues for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart).............. II-64

Table 19: World Recent Past, Current and Future Analysis for Biophotonics in Medical Therapeutics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-65

Table 20: World Historic Review for Biophotonics in Medical Therapeutics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............II-66

Table 21: World 14-Year Perspective for Biophotonics in Medical Therapeutics by Geographic Region - Percentage Breakdown of Revenues for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............II-67

Table 22: World Recent Past, Current and Future Analysis for Biophotonics in Medical Diagnostics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-68

Table 23: World Historic Review for Biophotonics in Medical Diagnostics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............II-69

Table 24: World 14-Year Perspective for Biophotonics in Medical Diagnostics by Geographic Region - Percentage Breakdown of Revenues for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............II-70

Table 25: World Recent Past, Current and Future Analysis for Other Medical Biophotonics Applications by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-71

Table 26: World Historic Review for Other Medical Biophotonics Applications by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............II-72

Table 27: World 14-Year Perspective for Other Medical Biophotonics Applications by Geographic Region - Percentage Breakdown of Revenues for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............II-73

Table 28: World Recent Past, Current and Future Analysis for Non-Medical Applications of Biophotonics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-74

Table 29: World Historic Review for Non-Medical Applications of Biophotonics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) II-75

Table 30: World 14-Year Perspective for Non-Medical Applications of Biophotonics by Geographic Region - Percentage Breakdown of Revenues for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............II-76

III. MARKET

1. THE UNITED STATES.............. III-1 A.Market Analysis.............. III-1 Outlook.............. III-1 Biophotonics for Medical Devices III-1 Life Science Research Tools Benefit from Photonics Technology III-2 Rapidly Aging Demographics: A Major Driving Factor III-2 Table 31: North American Elderly Population by Age Group (1975-2050) (includes corresponding Graph/Chart) III-3 Rising Incidences of Chronic Diseases Enhance Demand for Biophotonics.............. III-3 Cancer Prevalence Statistics in the US - Growth Opportunities for Biophotonics III-3 Table 32: New Cancer Cases in US by State: 2014 (includes corresponding Graph/Chart) III-4

Table 33: Number of Deaths Related to Major Types of Cancer in US by State: 2014 (includes corresponding Graph/Chart).............. III-5

Table 34: New Cancer Cases in the US by Gender and Affected Site: 2014 (includes corresponding Graph/Chart) III-6

Table 35: US Cancer Incidence for All Body Sites by Gender & Age Group (2013): New Cancer Cases for Males & Females for the Age groups Under 45 years; 45 years and Above; Under 65 years; and 65 years and Above (includes corresponding Graph/Chart) III-7 Prevalence of Diabetes Mellitus in North America III-7 Table 36: Prevalence of Diabetes Mellitus among 20-79 Yrs Age Group in North America and Caribbean (2014): Breakdown by Country/ Territory (in 000 People & %) III-8 Product Launches..............III-9 Strategic Corporate Developments III-10 Select Players.............. III-11 B.Market Analytics..............III-17 Table 37: US Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-17

Table 38: US Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-18

Table 39: US 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart).............. III-19

2. CANADA.............. III-20 A.Market Analysis.............. III-20 Outlook.............. III-20 Rising Incidence of Cancer - A Business Case for Biophotonics III-20 Table 40: New Cancer Cases in Canada by Gender and Affected Site: 2014 (includes corresponding Graph/Chart) III-21

Table 41: New Cancer Cases in Canada by Province: 2014 (includes corresponding Graph/Chart) III-22

Table 42: New Cancer Cases in Canada by Age Group: 2014 (includes corresponding Graph/Chart) III-23

Table 43: Cancer Related Deaths in Canada by Gender and Affected Site: 2014 (includes corresponding Graph/Chart) III-24

Table 44: Cancer Related Deaths in Canada by Province: 2014 (includes corresponding Graph/Chart) III-25

Table 45: Cancer Related Deaths in Canada by Age Group: 2014 (includes corresponding Graph/Chart) III-26 Increasing Penetration of DM - An Opportunity for Biophotonics III-26 Table 46: Prevalence of Diabetes Mellitus in Canada: 2014 III-27 Product Launch.............. III-27 B.Market Analytics..............III-28 Table 47: Canadian Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-28

Table 48: Canadian Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-29

Table 49: Canadian 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-30

3. JAPAN.............. III-31 A.Market Analysis.............. III-31 Outlook.............. III-31 Rising Cancer and Diabetes Cases Provide Growth Opportunity III-31 Table 50: Cancer Related Deaths by Age Groups: 2013 (includes corresponding Graph/Chart) III-32

Table 51: Prevalence of Diabetes Mellitus in Japan (2014) III-33 Select Players.............. III-33 B.Market Analytics..............III-34 Table 52: Japanese Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-34

Table 53: Japanese Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-35

Table 54: Japanese 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-36

4. EUROPE.............. III-37 A.Market Analysis.............. III-37 Market Overview.............. III-37 Aging Population & Rising Incidence of Chronic Diseases to Drive Growth.............. III-37 Table 55: Population Breakup by Age Group for Select European Countries: 2012 (as a Percentage of Total Population) (includes corresponding Graph/Chart) III-39 Cancer and Diabetes Mellitus in Europe: Key Statistics III-39 Table 56: European Predicted Cancer Deaths in 2014: Number of Deaths by Gender and Major Cancer Type (includes corresponding Graph/Chart)..............III-40

Table 57: Prevalence of Diabetes Mellitus among 20-79 Yrs Age Group in Europe by Country/Territory (2014) (In 000 People & %) (includes corresponding Graph/Chart) III-41 Product Launch.............. III-42 B.Market Analytics..............III-42 Table 58: European Recent Past, Current and Future Analysis for Biophotonics by Geographic Region - France, Germany, Italy, UK, Spain, Russia, and Rest of Europe Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-42

Table 59: European Historic Review for Biophotonics by Geographic Region - France, Germany, Italy, UK, Spain, Russia, and Rest of Europe Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-43

Table 60: European 14-Year Perspective for Biophotonics by Geographic Region - Percentage Breakdown of Revenues for France, Germany, Italy, UK, Spain, Russia, and Rest of Europe Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-44

Table 61: European Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-45

Table 62: European Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-46

Table 63: European 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-47

4a. FRANCE.............. III-48 A.Market Analysis.............. III-48 Outlook.............. III-48 Corporate Development..............III-48 CEA-LETI - A Key Player..............III-48 B.Market Analytics..............III-49 Table 64: French Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-49

Table 65: French Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-50

Table 66: French 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-51

4b. GERMANY.............. III-52 A.Market Analysis.............. III-52 Outlook.............. III-52 Strategic Corporate Developments III-52 Select Players.............. III-53 B.Market Analytics..............III-54 Table 67: German Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-54

Table 68: German Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-55

Table 69: German 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-56

4c. ITALY.............. III-57 Market Analysis.............. III-57 Table 70: Italian Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-58

Table 71: Italian Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-59

Table 72: Italian 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-60

4d. THE UNITED KINGDOM..............III-61 Market Analysis.............. III-61 Table 73: UK Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-62

Table 74: UK Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-63

Table 75: UK 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart).............. III-64

4e. SPAIN.............. III-65 A.Market Analysis.............. III-65 Outlook.............. III-65 Select Players.............. III-65 B.Market Analytics..............III-66 Table 76: Spanish Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-66

Table 77: Spanish Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-67

Table 78: Spanish 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-68

4f. RUSSIA.............. III-69 A.Market Analysis.............. III-69 Outlook.............. III-69 INJECT ENTERPRISE - A Major Player III-69 B.Market Analytics..............III-70 Table 79: Russian Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-70

Table 80: Russian Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-71

Table 81: Russian 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-72

4g. REST OF EUROPE.............. III-73 A.Market Analysis.............. III-73 Outlook.............. III-73 Key Players.............. III-73 B.Market Analytics..............III-75 Table 82: Rest of Europe Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-75

Table 83: Rest of Europe Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-76

Table 84: Rest of Europe 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-77

5. ASIA-PACIFIC.............. III-78 A.Market Analysis.............. III-78 Outlook.............. III-78 Increasing Prevalence of Diabetes to Drive Biophotonics Market III-78 Diabetes Statistics in Asia-Pacific - Opportunity Indicators III-79 Table 85: Prevalence of Diabetes Mellitus among 20-79 Yrs Age Group in Southeast Asia (2014): Breakdown by Country/ Territory (in 000 People & %) (includes corresponding Graph/Chart).............. III-79

Table 86: Prevalence of Diabetes Mellitus among 20-79 Yrs Age Group in Western Asia by Country/Territory (2014) (In 000s & %).............. III-80

Table 87: Incidence of Type 1 Diabetes in Children by Select Countries in Western Pacific (2012) (includes corresponding Graph/Chart) III-81 China.............. III-81 Strategic Corporate Developments III-82 Zecotek Photonics, Inc. - A Major Player III-82 B.Market Analytics..............III-83 Table 88: Asia-Pacific Recent Past, Current and Future Analysis for Biophotonics by Geographic Region - China, India, and Rest of Asia-Pacific Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-83

Table 89: Asia-Pacific Historic Review for Biophotonics by Geographic Region - China, India, and Rest of Asia-Pacific Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-84

Table 90: Asia-Pacific 14-Year Perspective for Biophotonics by Geographic Region - Percentage Breakdown of Revenues for China, India, and Rest of Asia-Pacific Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-85

Table 91: Asia-Pacific Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-86

Table 92: Asia-Pacific Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-87

Table 93: Asia-Pacific 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-88

6. LATIN AMERICA.............. III-89 A.Market Analysis.............. III-89 Outlook.............. III-89 Rising Incidence of Diabetes in Latin America - Opportunity Indicator.............. III-89 Table 94: Prevalence of Diabetes Mellitus in South & Central America (2013 & 2035): Breakdown by Country and Age Group (In 000 People & %) (includes corresponding Graph/Chart).............. III-90 B.Market Analytics..............III-91 Table 95: Latin America Recent Past, Current and Future Analysis for Biophotonics by Geographic Region - Brazil, and Rest of Latin America Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-91

Table 96: Latin America Historic Review for Biophotonics by Geographic Region - Brazil, and Rest of Latin America Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-92

Table 97: Latin America 14-Year Perspective for Biophotonics by Geographic Region - Percentage Breakdown of Revenues for Brazil, and Rest of Latin America Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-93

Table 98: Latin America Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-94

Table 99: Latin America Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-95

Table 100: Latin America 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-96

7. REST OF WORLD.............. III-97 A.Market Analysis.............. III-97 Outlook.............. III-97 Increasing Incidence of Chronic Conditions: Opportunity for Biophotonics.............. III-97 Diabetes Prevalence Statistics III-98 Table 101: Prevalence of Diabetes Mellitus among 20-79 Yrs Age Group in Africa (2014): Breakdown by Country/Territory (in 000 People & %) (includes corresponding Graph/Chart) III-98

Table 102: Prevalence of Diabetes Mellitus in Middle East & North Africa (2014): Breakdown by Country/Territory and Age Group (in 000 People & %) (includes corresponding Graph/Chart).............. III-99

Table 103: African Population and Diabetes Prevalence Statistics (2013) - Select Regions with High Prevalence of Diabetes for Various Age Groups (20-39, 40-59, and 60-79) and Gender (includes corresponding Graph/Chart) III-100

Table 104: Middle East and North African Population and Diabetes Prevalence Statistics (2013 Estimates) - Select Regions with High Prevalence of Diabetes for Various Age Groups (20-39, 40-59, and 60-79) and Gender (includes corresponding Graph/Chart) III-101 Product Launches..............III-102 Lumenis ltd. (Israel) - A Key Player III-102 B.Market Analytics..............III-103 Table 105: Rest of World Recent Past, Current and Future Analysis for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-103

Table 106: Rest of World Historic Review for Biophotonics by End-Use Sector - Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-104

Table 107: Rest of World 14-Year Perspective for Biophotonics by End-Use Sector - Percentage Breakdown of Revenues for Medical (Therapeutics, Diagnostics, and Others) and Non-Medical Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-105

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 85 (including Divisions/Subsidiaries - 88)

The United States (45) Canada (5) Japan (4) Europe (30) - France (3) - Germany (9) - The United Kingdom (3) - Spain (2) - Rest of Europe (13) Asia-Pacific (Excluding Japan) (2) Middle East (2)
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