2013-04-01

New page

===Welcome to the Registry of Standard Biological Parts.===

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'''The Registry is a [http://partsregistry.org/cgi/partsdb/Statistics.cgi continuously growing] collection of genetic parts that can be mixed and matched to build synthetic biology devices and systems. Founded in 2003 at MIT, the Registry is part of the Synthetic Biology community's efforts to make biology easier to engineer. It provides a resource of available genetic parts to [http://igem.org iGEM] teams and academic labs. You can [http://igem.org register a new lab here].'''

The Registry is based on the principle of "get some, give some". Registry users benefit from using the parts and information available from the Registry in designing their engineered biological systems. In exchange, the expectation is that Registry users will, in turn, contribute back information and data on existing parts and new parts that they make to grow and improve this community resource.

{|

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{|

|align='center' width=125px | [http://partsregistry.org/Catalog http://partsregistry.org/wiki/images/e/e0/Montage_70.png]

|align='center' width=125px | {{Click || image=Plasmidhelpbutton.png | link=Help:Contents | width=70px | height=70px }}

|align='center' width=125px | {{Click || image=Proteinlocalizationsequencebutton.png | link=User accounts | width=70px | height=70px }}

|align='center' width=125px | [http://partsregistry.org/assembly/libraries.cgi http://partsregistry.org/wiki/images/5/55/DNArepositories70.png]

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|align='center' | '''[[Catalog|Catalog of parts & devices]]'''

|align='center' | '''[[Help:Contents|Help]]'''

|align='center' | [http://igem.org '''Users & groups''']

|align='center' | '''[http://partsregistry.org/cgi/assembly/libraries.cgi DNA repositories]'''

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|valign='top' border="1" style="border:#c9c9c9 0px solid; margin: 1em 1em 1em 0; border-collapse: collapse;" |

=== Registry tools===

*'''[http://partsregistry.org/cgi/partsdb/search.cgi Search parts]''' '''[[Help:Search|(?)]]'''

*'''[[Add a Part to the Registry|Add a part]]'''

*'''[[Help:Requesting Parts | Request a part]]'''

*'''[http://partsregistry.org/cgi/dna_transfer/index.cgi Send parts to the Registry]'''

*'''[http://partsregistry.org/cgi/sequencing/index.cgi Sequence analysis]'''

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===Registry changes===

This year (2013) iGEM Headquarters is making some major changes to the Registry. We would like to let you know what to expect.

First, we are going to dramatically prune the collection of parts so the excellent parts in the collection are

not lost among the weeds that are also in the collection. As a community collection, the Registry contains every part entered by anyone.

This includes parts with no sequence, no description, and even parts with a description such as ''delete me''. Many of the parts are

old, poorly documented, and unused.

We are going to discontinue thousands of parts.

Second, iGEMers have sent us ''samples'' that contain ''parts''. In the past, we took a passive approach to quality control. We sent out a distribution

and sent parts on request without concern to the quality of the sample. In the case of the distribution, we sequenced each sample and

tested the plasmid backbone by cutting and running on a gel as well as testing growth in several antibiotics. However, we sent the sample

without regard for this information, trusting the iGEMer to evaluate the QC information themselves.

This year's distribution will consist of parts that are sequence verified. In addition, we are transferring parts as needed to pSB1C3.

Third, we are changing the way we think about the status of a part (and sample). The term ''Available'' was always misleading. Was the part

released by the team (was it complete), was the DNA available, was it correct? We used the fact that a team sent a part to indicate that it was an important part and should be included in tables and widely considered

We are introducing the concept of ''Releasing a Part''. This means that the author of the part says it is ready and important. Separately, we are introducing the concept of the status of a sample. Is it in a distribution, can you order it, or not. Perhaps it is of questionable quality or is unsequenced.

Along with this, we are introducing a new Sample page with better information about the sample.

Fourth, we are upgrading the web site. The new site will be more modern and easier to use. We will improve the search capability and introduce a new category browser to make it easier to find the part you want.

These and many other changes are taking place now and will continue through the year. We hope you like the new Registry.

-- Randy

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===Related resources & links===

*'''[http://igem.org iGEM]'''

*'''[http://biobricks.org The BioBricks Foundation]'''

*'''[http://openwetware.org OpenWetWare]'''

*'''[http://www.neb.com/nebecomm/products/productE0546.asp BioBrick Assembly Kit]''' and [http://ginkgobioworks.com/support/ online step-by-step assembly manual].

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