Intraglottal velocity and pressure
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 47 δευτερόλεπτα
*Intraglottal velocity and pressure measurements in a hemilarynx model.* J Acoust Soc Am. 2015 Feb;137(2):935 Authors: Oren L, Gutmark E, Khosla S Abstract Determining the mechanisms of self-sustained oscillation of the vocal folds requires characterization of the pressures produced by intraglottal aerodynamics. Because most of the intraglottal aerodynamic forces cannot be measured in a tissue model of the larynx, current understanding of vocal fold vibration mechanism is derived from mechanical, analytical, and computational models. Previous studies have computed intraglottal pressure...περισσότερα »
Emergency cricothyrotomy
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 47 δευτερόλεπτα
*Every Surgical Resident Should Know How to Perform a Cricothyrotomy: An Inexpensive Cricothyrotomy Task Trainer for Teaching and Assessing Surgical Trainees.* J Surg Educ. 2015 Feb ; https://www.youtube.com/watch?v=_VFJGkJy1G8 Authors: Aho JM, Thiels CA, AlJamal YN, Ruparel RK, Rowse PG, Heller SF, Farley DR Abstract OBJECTIVE: Emergency cricothyrotomy is a rare but potentially lifesaving procedure. Training opportunities for surgical residents to learn this skill are limited, and many graduating residents have never performed one during their training. We aimed to develop and valida...περισσότερα »
Epigenome engineering in cancer
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 47 δευτερόλεπτα
*: fairytale or a realistic path to the clinic?* Front Oncol. 2015;5:22 Authors: Falahi F, Sgro A, Blancafort P Abstract Epigenetic modifications such as histone post-transcriptional modifications, DNA methylation, and non-protein-coding RNAs organize the DNA in the nucleus of eukaryotic cells and are critical for the spatio-temporal regulation of gene expression. These epigenetic modifications are reversible and precisely regulated by epigenetic enzymes. In addition to genetic mutations, epigenetic modifications are highly disrupted in cancer relative to normal tissues. Many epigenet... περισσότερα »
Amyotrophic lateral sclerosis (ALS) and neck muscle weakness : Elastic head support
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 47 δευτερόλεπτα
[image: http:--www.rehab.research.va.gov-pmbutto] *Elastic head support for persons with amyotrophic lateral sclerosis.* J Rehabil Res Dev. Authors: Hansen A, Bedore B, Nickel E, Hanowski K, Tangen S, Goldish G Abstract This article describes an inexpensive elastic head support for persons with amyotrophic lateral sclerosis (ALS) and neck muscle weakness and also presents a case series to examine its effectiveness. The device offers support to the head while the user is seated, standing, and walking, providing support for persons in various stages of ALS. The head support system was t... περισσότερα »
VE showed high reproducibility and reliability in the classification of sequential swallowing types
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 47 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] *Classification of sequential swallowing types using videoendoscopy with high reproducibility and reliability.* Am J Phys Med Rehabil. 2015 Authors: Susa C, Kagaya H, Saitoh E, Baba M, Kanamori D, Mikushi S, Ozaki K, Uematsu H, Minakuchi S Abstract OBJECTIVE: This study aimed to classify sequential swallowing types using videoendoscopy (VE) avoiding radiation exposure and compare the results using videofluoroscopy (VF). DESIGN: Twenty-one healthy adults simultaneously underwent VF and VE during sequential straw drinking. Each discrete ... περισσότερα »
Non-syndromic orofacial clefts
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 47 δευτερόλεπτα
http://goo.gl/9N6ZvS *Prevalence of non-syndromic orofacial clefts among Jews and Arabs, by type, site, gender and geography: a multi-center study in Israel.* Isr Med Assoc J. Authors: Shapira Y, Haklai Z, Blum I, Shpack N, Amitai Y Abstract BACKGROUND: Orofacial clefts are the most common craniofacial congenital malformations, with significant anatomic, ethnic, racial and gender differences. OBJECTIVES: To investigate the prevalence, distribution and characteristic features of various types of non-syndromic clefts among Israeli Jews and Arabs. METHODS: We conducted a retrospective mul... περισσότερα »
Trachea esophageal puncture (TEP)
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
*Management of aphonic patients following total laryngectomy and trachea esophageal puncture.* Isr Med Assoc J. Authors: Benyamini L, Gil Z, Cohen JT Abstract BACKGROUND: Trachea esophageal puncture (TEP) is performed following total laryngectomy to allow speech and communication. The most common reason for long-term speech failure in this population is hypertonicity of the constrictor muscle. OBJECTIVES: To present our experience with the treatment of aphonic patients after total laryngectomy and TEP and suggest a protocol for treatment. METHODS: Of 50 patients who underwent total la... περισσότερα »
Transcranial non-invasive brain stimulation in swallowing rehabilitation following stroke
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
* - A review of the literature.* Physiol Behav. 2015 Feb ; Authors: Doeltgen SH, Bradnam L, Young J, Fong E Abstract BACKGROUND: This descriptive review of the literature outlines the current evidence-base underpinning the potential of transcranial brain stimulation techniques to modulate swallowing function in healthy individuals and in treating post-stroke dysphagia. METHODS: Published research was identified by review of scientific databases (Scopus, Medline Ovid, Science Direct, AMED and Google Scholar) using relevant keywords. In addition, the reference lists of identified articl... περισσότερα »
Visual-induced expectations modulate auditory cortical responses
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
Front Neurosci. 2015;9:11 Authors: van Wassenhove V, Grzeczkowski L Abstract Active sensing has important consequences on multisensory processing (Schroeder et al., 2010). Here, we asked whether in the absence of saccades, the position of the eyes and the timing of transient color changes of visual stimuli could selectively affect the excitability of auditory cortex by predicting the "where" and the "when" of a sound, respectively. Human participants were recorded with magnetoencephalography (MEG) while maintaining the position of their eyes on the left, right, or center of the scree...περισσότερα »
Oncotarget http://www.impactjournals.com/oncotarget/
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 14 δευτερόλεπτα
Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction. *Lamb R1,2, Harrison H1,2, Smith DL3, Townsend PA1, Jackson T1, Ozsvari B1,2, Martinez-Outschoorn UE4, Pestell RG4, Howell A1,2, Lisanti MP1,2, Sotgia F1,2.* Author information Abstract *We have used an unbiased proteomic profiling strategy to identify new potential therapeutic targets in tumor-initiating cells (TICs), a.k.a., cancer stem cells (CSCs). Towards this end, the proteomes of mammospheres from two breast cancer cell lines were ... περισσότερα »
Black Stain and Dental Caries
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα
: A Review of the Literature via BioMed Research International Black stain is characterized as a dark line or an incomplete coalescence of dark dots localized on the cervical third of the tooth. Over the last century, the etiology of black stain has been the subject of much debate. Most of the studies concerning this issue were conducted in pediatric population. According to the reviewed articles published between 2001 and 2014, the prevalence of black stain varies from 2.4% to 18% with equal sex distribution. The majority of the authors confirm the correlation between the presence o... περισσότερα »
Acute porphyria and Arnold Chiari malformation
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα
*Acute porphyria in a patient with Arnold Chiari malformation.* Am J Case Rep. 2015;16:99-103 Authors: Shen J, O'Keefe K, Webb LB, DeGirolamo A Abstract BACKGROUND: Acute porphyria and Arnold Chiari malformation are both uncommon genetic disorders without known association. The insidious onset, non-specific clinical manifestations, and precipitating factors often cause diagnosis of acute porphyria to be missed, particularly in patients with comorbidities. CASE REPORT: A women with Arnold Chiari malformation type II who was treated with oxybutynin and antibiotics, including Bactrim for ...περισσότερα »
Bony fusion in a chronic cervical bilateral facet dislocation
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 19 δευτερόλεπτα
Am J Case Rep. 2015;16:104-8 Authors: Bodman A, Chin L Abstract Background Cervical facet dislocation injuries typically present shortly after occurrence due to the pain and neurologic deficit that can be associated with this injury. Bilateral dislocations of the facet joint require prompt evaluation, reduction, and surgical intervention. Rare case reports present bilateral dislocations presenting in a delayed fashion. Case Report We report the case of a 60-year-old male who presented with mild neck pain 1 year after initial injury. Computed topography of the cervical spine showed he... περισσότερα »
Neurodevelopmental disorders : Effect of bisphenol A
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 19 δευτερόλεπτα
Effect of bisphenol A on Drosophila melanogaster behavior – A new model for the studies on neurodevelopmental disorders via ScienceDirect Publication: Behavioural Brain Research Publication date: 1 May 2015 *Source:*Behavioural Brain Research, Volume 284 Author(s): Kulbir Kaur , Anne F. Simon , Ved Chauhan , Abha Chauhan Developmental disorders such as autism and attention deficit hyperactivity disorder (ADHD) appear to have a complex etiology implicating both genetic and environmental factors. Bisphenol A (BPA), a widely used chemical in the plastic containers and in the linings of foo... περισσότερα »
25-hydroxyvitamin D [25(OH)D] and obesity and type 2 diabetes
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 19 δευτερόλεπτα
*Serum 25-Hydroxyvitamin D and Adipose Tissue Vitamin D Receptor Gene Expression: Relationship With Obesity and Type 2 Diabetes.* J Clin Endocrinol Metab. 2015 Feb 23;:jc20143016 Authors: Clemente-Postigo M, Muñoz-Garach A, Serrano M, Garrido-Sánchez L, Bernal-López MR, Fernández-García D, Moreno-Santos I, Garriga N, Castellano-Castillo D, Camargo A, Fernandez-Real JM, Cardona F, Tinahones FJ, Macías-González M Abstract Context: The relationship between 25-hydroxyvitamin D [25(OH)D] and obesity and type 2 diabetes is not completely understood. Vitamin D receptor (VDR) expression in ad... περισσότερα »
The patency of the inferior cochlear vein (ICV) may be challenged in cochlear implantation (CI)
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 19 δευτερόλεπτα
*The inferior cochlear vein: surgical aspects in cochlear implantation.* Eur Arch Otorhinolaryngol. 2015 Feb 21; Authors: Guo R, Zhang H, Chen W, Zhu X, Liu W, Rask-Andersen H Abstract *The patency of the inferior cochlear vein (ICV) may be challenged in cochlear implantation (CI) due to its location near the round window (RW).* This may be essential to consider during selection of different trajectories for electrode insertion aiming at preserving residual hearing. Venous blood from the human cochlea is drained through the ICV. The vein also drains blood from the modiolus containing t... περισσότερα »
Superior subperiosteal orbital abscess (SSPOA)
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 19 δευτερόλεπτα
*Management of superior subperiosteal orbital abscess.* Eur Arch Otorhinolaryngol. 2015 Feb 21; Authors: Gavriel H, Jabrin B, Eviatar E Abstract A superior subperiosteal orbital abscess (SSPOA) is a collection of purulent material between the periorbit and the superior bony orbital wall, and is typically a complication of frontal sinusitis. SSPOA is characteristically managed by classic external surgical drainage. The aim of our study was to assess the role of surgical intervention in SSPOA. A retrospective medical chart review of patients diagnosed with SSPOA secondary to rhinosinusi... περισσότερα »
Retro-sigmoid approach to resection of vestibular schwannoma : Long-term vestibulocochlear functional outcomes
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 19 δευτερόλεπτα
*Long-term vestibulocochlear functional outcome following retro-sigmoid approach to resection of vestibular schwannoma.* Eur Arch Otorhinolaryngol. 2015 Feb 21; Authors: Abboud T, Regelsberger J, Matschke J, Jowett N, Westphal M, Dalchow C Abstract The objective of this study was to evaluate long-term vestibulocochlear functional outcomes of patients operated for unilateral vestibular schwannoma via the retro-sigmoid approach. Patients who underwent vestibular schwannoma resection via retro-sigmoid approach between 2004 and 2008 at our institution, without prior surgical or radio-surg...περισσότερα »
Xanthogranulomatous hypophysitis (XGH)
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 19 δευτερόλεπτα
Xanthogranulomatous hypophysitis: a rare and often mistaken pituitary lesion by Jaya Sujatha Gopal-Kothandapani via 'Thyroxine (T4)' - EDM Case Reports Search SummaryXanthogranulomatous hypophysitis (XGH) is a very rare form of pituitary hypophysitis that may present both clinically and radiologically as a neoplastic lesion. It may either be primary with an autoimmune aetiology and can occur in isolation or as a part of autoimmune systemic disease or secondary as a reactive degenerative response to an epithelial lesion (e.g. craniopharyngioma (CP), Rathke's cleft cyst, germinoma and ...περισσότερα »
Eosinophilic granulomatosis with polyangiitis (EGPA)
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 19 δευτερόλεπτα
Factors that predict in-hospital mortality in eosinophilic granulomatosis with polyangiitis by Wakae Hasegawa, Yasuhiro Yamauchi, Hideo Yasunaga, Mitsuhiro Sunohara, Taisuke Jo, Hiroki Matsui, Kiyohide Fushimi, Kazutaka Takami, Takahide Nagase viaAllergy Abstract Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic small-vessel vasculitis associated with asthma, eosinophilia, and necrotizing vasculitis. EGPA is potentially life-threatening and often involves peripheral neuropathies, peptic ulcers, cerebral vessel disease, and cardiovascular disease. How...περισσότερα »
Asthma phenotypes and lung function
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 20 δευτερόλεπτα
up to 16 years of age - the BAMSE cohort by Jenny Hallberg, Per Thunqvist, Erica S Schultz, Inger Kull, Matteo Bottai, Anne-Sophie Merritt, Flaminia Chiesa, Per M Gustafsson, Erik Melén via Allergy Abstract Background Asthma is a disease affecting many locations throughout the airway. Most studies have used spirometry as the primary assessment of airway obstruction, a method that may be less sensitive in regard to peripheral airway obstruction. The aim of the current study was to elucidate the associations between asthma phenotypes based on age of onset and duration of symptoms and;...περισσότερα »
Serum periostin levels correlate with airway hyperresponsiveness to methacholine and mannitol
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 20 δευτερόλεπτα
in children with asthma by Joon-Sup Song, Jueng-Sup You, Soo-In Jeong, Seong Yang, Il-Tae Hwang, Yeong-Gwan Im, Hey-Sung Baek, Ho-Yeon Kim, Kenji Izuhara via Allergy Asthma is a complex clinical syndrome characterized by variable airflow obstruction (some of which can be permanent), airway hyperresponsiveness (AHR), and cellular inflammation. It is a heterogeneous disorder, exhibiting multiple phenotypes, reflected by the many clinical aspects of the disease (1-5). Recent advances in the identification of serum biomarkers for asthma are important in its diagnosis, including determin...περισσότερα »
Narrow band imaging (NBI) in visualizing laryngeal papillomatosis (LP)
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 20 δευτερόλεπτα
Article in Press The Utility of Narrow Band Imaging in the Treatment of Laryngeal Papillomatosis in Awake Patients Matthew C. Ochsner[image: correspondence][image: email] , Adam M. Klein *Journal of Voice* DOI: http://dx.doi.org/10.1016/j.jvoice.2014.08.002 SummaryObjective To determine the value of narrow band imaging (NBI) in visualizing laryngeal papillomatosis (LP), specifically in the awake patient. Study Design Retrospective chart review followed by trial of intervention. Methods Ten patients treated for LP in the awake setting were included in the study. Still shots of the same... περισσότερα »
The acoustic values obtained for the older group with perceptually normal voices
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 20 δευτερόλεπτα
Article in Press Multidimensional Voice Data on Participants With Perceptually Normal Voices From Ages 60 to 80: A Preliminary Acoustic Reference for the Elderly Population Natalie Schaeffer[image: correspondence][image: email] , Melissa Knudsen , Ashley Small Department of Speech Communication Arts and Sciences, Brooklyn College, Brooklyn, New York *Journal of Voice* DOI: http://dx.doi.org/10.1016/j.jvoice.2014.10.003 Publication stage: In Press Corrected Proof SummaryObjective The purpose of this study was to provide a preliminary acoustic reference for an elderly population (aged ... περισσότερα »
Children's Dysphonia
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 20 δευτερόλεπτα
Article in Press Parents' Evaluations of Their Children's Dysphonia: The Mamas and the Papas Ofer Amir[image: correspondence][image: email] , Michael Wolf , Liron Mick , Omer Levi , Adi Primov-Fever *Journal of Voice* DOI: http://dx.doi.org/10.1016/j.jvoice.2014.09.021 Publication stage: In Press Corrected Proof SummaryObjectives This study aimed to evaluate the validity and reliability of a Hebrew translation of the Pediatric Voice Handicap Index (pVHI). It also examined differences between mothers and fathers in evaluating their child's dysphonia. Study Design Observational design... περισσότερα »
Inhaled Steroids : Voice Assessment
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 30 δευτερόλεπτα
Article in Press Voice Assessment After Treatment of Subacute and Chronic Cough With Inhaled Steroids Arzu Tuzuner[image: correspondence][image: email] , Sule Demirci , Gulden Bilgin , Ali Cagli , Filiz Aydogan , Kursat Murat Ozcan , Etem Erdal Samim *Journal of Voice* DOI: http://dx.doi.org/10.1016/j.jvoice.2014.09.007 Publication stage: In Press Corrected Proof SummaryIntroduction Inhaled steroids are widely used for persistent cough treatment. Although the side effects of long-term inhaled steroids have been well described in the literature, their laryngeal side effects after s... περισσότερα »
The learning and teaching of different singing styles
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 30 δευτερόλεπτα
Article in Press Tuning Features of Chinese Folk Song Singing: A Case Study of Hua'er Music Yang Yang[image: correspondence][image: email] , Graham Welch , Johan Sundberg , Evangelos Himonides *Journal of Voice* DOI: http://dx.doi.org/10.1016/j.jvoice.2014.08.013 Objectives The learning and teaching of different singing styles, such as operatic and Chinese folk singing, was often found to be very challenging in professional music education because of the complexity of varied musical properties and vocalizations. By studying the acoustical and musical parameters of the singing voice... <a href="http://onlinemedicaljournals.blogspot.com/2015/02/the-learning-and-teaching-of-different.html" style="color: #1155cc; margin: 0px; padding: 0px; tex