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LITERATURE UPDATE February 20, 2014 – February 26, 2014 Literature search for biomech* or locomot* Jason R. Franz, Ph.D. Neuromuscular Biomechanics Laboratory http://sites.google.com/site/jasonrfranz/ http://uwnmbl.engr.wisc.edu/ University...

Background: Rats exhibit extremely limited motor function recovery after total transection of the spinal cord (SCT). We previously reported that SM-216289, a semaphorin3A inhibitor, enhanced axon regeneration and motor function recovery in SCT adult...

Background: Central sensitization in the spinal cord requires glutamate receptor activation and intracellular Ca2+ mobilization. We used Fura-2AM bulk loading of mouse slices together with wide-field Ca2+ imaging to measure glutamate-evoked increases...

Lipocalin 2 (LCN2), which is also known as 24p3 and neutrophil gelatinase-associated lipocalin (NGAL), binds small, hydrophobic ligands and interacts with cell surface receptor 24p3R to regulate diverse cellular processes. In the present study, we examined...

At the request of several members, I am writing a summary of conus medullaris injuries, its clinical manifestations and what potential therapies are being developed to restore function in such injuries. Most spinal cord injuries involve the cervical...