A novel technique to correct kyphosis in cervical myelopathy due to continuous-type ossification of the posterior longitudinal ligament

We aimed in this study to establish a new technique for the treatment of patients with cervical myelopathy that results from multilevel OPLL and kyphosis.

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Contralateral osteotomy of the pedicle and posterolateral elements for en bloc resection: a technique for oncological resection of posterolateral spinal tumors

Viren S. Vasudeva, MD1, Alexander E. Ropper, MD2, Samuel Rodriguez, MD3, Kyle C. Wu, MD1, and John H. Chi, MD, MPH1,4 1Department of Neurosurgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts; 2Department of Neurosurgery, Baylor College of Medicine, Houston, Texas; 3Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California; and 4Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts

Pages 275-281

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Spine stereotactic radiosurgery for the treatment of multiple myeloma

Jacob A. Miller, BS1, Ehsan H. Balagamwala, MD2, Samuel T. Chao, MD2,3, Todd Emch, MD4, John H. Suh, MD2,3, Toufik Djemil, PhD5, and Lilyana Angelov, MD3,6 1Cleveland Clinic Lerner College of Medicine, 2Department of Radiation Oncology, 3Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, 4Department of Diagnostic Radiology, and 6Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio; and 5Department of Radiation Oncology, Cleveland Clinic Florida, Weston, Florida

Pages 282-290

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Malignant peripheral nerve sheath tumors of the spine: results of surgical management from a multicenter study

Dean Chou, MD1, Mark H. Bilsky, MD2, Alessandro Luzzati, MD3, Charles G. Fisher, MD, MHSc4, Ziya L. Gokaslan, MD5, Laurence D. Rhines, MD6, Mark B. Dekutoski, MD7, Michael G. Fehlings, MD8, Ravi Ghag, MD4, Peter Varga, MD9, Stefano Boriani, MD10, Niccole M. Germscheid, MSc11, Jeremy J. Reynolds, MBChB12, and the AOSpine Knowledge Forum Tumor 1Department of Neurosurgery, University of California, San Francisco, California; 2Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, New York; 3Department of Orthopedics, Istituto Ortopedico Galeazzi, Milan, Italy; 4Department of Orthopaedics, University of British Columbia, Vancouver, Canada; 5Department of Neurosurgery, Brown University, Providence, Rhode Island; 6Department of Neurosurgery, MD Anderson Cancer Center, Houston, Texas; 7Department of Orthopedics, The CORE Institute, Phoenix, Arizona; 8Department of Neurosurgery, University of Toronto, Ontario, Canada; 9Department of Orthopedics, National Center for Spinal Disorders, Budapest, Hungary; 10Department of Orthopedics, The Rizzoli Institute, Bologna, Italy; 11AOSpine International, Davos, Switzerland; and 12Department of Orthopaedics, Oxford University Hospitals, Oxford, United Kingdom

Pages 291-298

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Consensus guidelines for postoperative stereotactic body radiation therapy for spinal metastases: results of an international survey

Kristin J. Redmond, MD, MPH1, Simon S. Lo, MD2, Scott G. Soltys, MD3, Yoshiya Yamada, MD4, Igor J. Barani, MD5, Paul D. Brown, MD6, Eric L. Chang, MD7, Peter C. Gerszten, MD8, Samuel T. Chao, MD9, Robert J. Amdur, MD10, Antonio A. F. De Salles, MD, PhD11, Matthias Guckenberger, MD12, Bin S. Teh, MD13, Jason Sheehan, MD, PhD14, Charles R. Kersh, MD15, Michael G. Fehlings, MD, PhD, FRCSC16, Moon-Jun Sohn, MD, PhD17, Ung-Kyu Chang, MD18, Samuel Ryu, MD19, Iris C. Gibbs, MD3, and Arjun Sahgal, MD, FRCPC20 1Department of Radiation Oncology and Molecular Radiation Sciences, The John Hopkins University, Baltimore, Maryland; 2Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center; 9Department of Radiation Oncology, Rose Ella Burkhardt Brain Tumor and Neurooncology Center, Cleveland Clinic, Cleveland, Ohio; 3Department of Radiation Oncology, Stanford Cancer Institute, Stanford University, Stanford; 5Department of Radiation Oncology, University of California, San Francisco; 7Department of Radiation Oncology, Norris Cancer Center and Keck School of Medicine at University of Southern California; 11Department of Neurological Surgery, Brain Research Institute, University of California, Los Angeles, California; 4Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York; 19Department of Radiation Oncology, Stony Brook Cancer Center, Stony Brook, New York; 6Department of Radiation Oncology, MD Anderson Cancer Center; 13Department of Radiation Oncology, Houston Methodist Hospital, Cancer Center and Research Institute, Weill Cornell Medical College, Houston, Texas; 8Department of Neurological Surgery and Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; 10Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida; 12Department of Radiation Oncology, University of Zurich, Switzerland; 14Department of Neurological Surgery, University of Virginia Health System, Charlottesville; 15Department of Radiation Oncology, Riverside Radiation Oncology Specialists, Newport News, Virginia; 16Division of Neurosurgery and Spine Program, Toronto Western Hospital, University of Toronto; 20Department of Radiation Oncology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Ontario, Canada; 17Department of Neurological Surgery, Radiosurgery Center, Inje University Ilsan Paik Hospital, College of Medicine, Goyang; and 18Department of Neurosurgery, Korea Institute of Radiological and Medical Sciences, Seoul, South Korea

Pages 299-306

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Bilateral C-1 lateral mass reconstruction following radical resection of a giant osteoblastoma of the atlas: case report

Iulia Peciu-Florianu, MD1, Gopalakrishnan Chittur Viswanathan, MCh1, Juan Barges-Coll, MD1, Gabriel A. Castillo-Velázquez, MD4, Pierre-Yves Zambelli, MD, PhD2,3, and John M. Duff, MD1,3 1Neurosurgical Service, Department of Clinical Neurosciences and 2Division of Paediatric Orthopedics, University Hospital of Lausanne; 3Faculty of Biology and Medicine, University of Lausanne, Switzerland; and 4Neurosurgical Service, Centro Médico Puerta de Hierro, Guadalajara, Mexico

Pages 307-312

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Radiofrequency ablation of spinal osteoid osteoma: a prospective study

Joe Faddoul, MD2, Yara Faddoul, MD1, Sandra Kobaiter-Maarrawi, PhD1, Ronald Moussa, MD2, Tony Rizk, MD2, Georges Nohra, MD2, Nabil Okais, MD2, Elie Samaha, MD2, and Joseph Maarrawi, MD, PhD1,2 1Laboratory of Neurosciences, Faculty of Medicine (PTS), St. Joseph University; and 2Department of Neurosurgery, Hôtel-Dieu de France Hospital, Beirut, Lebanon

Pages 313-318

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Successful treatment of mixed yolk sac tumor and mature teratoma in the spinal cord: case report

Akitake Mukasa, MD, PhD1,, Shunsuke Yanagisawa, MD1, Kuniaki Saito, MD1, Shota Tanaka, MD1, Keisuke Takai, MD, PhD1,5, Junji Shibahara, MD, PhD2, Masachika Ikegami, MD3, Yusuke Nakao, MD3,6, Katsushi Takeshita, MD, PhD3,7, Masao Matsutani, MD, PhD4, and Nobuhito Saito, MD, PhD1Departments of 1Neurosurgery, 2Pathology, and 3Orthopaedic Surgery and Spinal Surgery, The University of Tokyo Hospital, Tokyo; and 4Department of Neuro-Oncology/Neurosurgery, Saitama Medical University International Medical Center, Hidaka, Japan

Pages 319-324

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A novel technique to correct kyphosis in cervical myelopathy due to continuous-type ossification of the posterior longitudinal ligament

Dong-Ho Lee, MD, PhD, Youn-Suk Joo, MD, Chang Ju Hwang, MD, PhD, Choon Sung Lee, MD, PhD, and Jae Hwan Cho, MDDepartment of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

Pages 325-330

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Revisiting the differences between irreducible and reducible atlantoaxial dislocation in the era of direct posterior approach and C1–2 joint manipulation

Arsikere N. Deepak, MS1, Pravin Salunke, MCh1, Sushanta K. Sahoo, MCh1, Prashant K. Prasad, MS1, and Niranjan K. Khandelwal, MD2Departments of 1Neurosurgery and 2Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Pages 331-340

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C-2 arteriovenous fistula presenting as a pathologic hangman’s fracture: case report

Rajeev D. Sen, BA, Carolina Gesteira Benjamin, MD, Howard A. Riina, MD, and Donato Pacione, MDNew York University School of Medicine, New York, New York

Pages 341-345

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Lateral mass screw stimulation thresholds in posterior cervical instrumentation surgery: a predictor of medial deviation

Bayard Wilson, BA1,, Erik Curtis, MD2, Brian Hirshman, MD, MS2, Ahmet Oygar, MD2, Karen Chen, MD3, Brandon C. Gabel, MD2, Florin Vaida, PhD4, David W. Allison, PhD5, and Joseph D. Ciacci, MD2 1School of Medicine, 2Department of Neurosurgery, 3Department of Radiology, 4Department of Family Medicine and Public Health, Division of Biostatistics and Bio-informatics, and 5Department of Interventional Neurophysiology, University of California, San Diego, California

Pages 346-352

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Lumbar decompression in the elderly: increased age as a risk factor for complications and nonhome discharge

Meghan E. Murphy, MD1,2, Hannah Gilder, BS1,2, Patrick R. Maloney, MD1,2, Brandon A. McCutcheon, MD, MPP1,2, Lorenzo Rinaldo, MD, PhD1,2, Daniel Shepherd, MD1,2, Panagiotis Kerezoudis, MD1,2, Daniel S. Ubl, MPH3, Cynthia S. Crowson, MS3, William E. Krauss, MD1, Elizabeth B. Habermann, PhD, MPH3, and Mohamad Bydon, MD1,2 1Department of Neurologic Surgery, Mayo Clinic; 2Mayo Clinic Neuro-Informatics Laboratory; and 3Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota

Pages 353-362

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High-dose tranexamic acid reduces intraoperative and postoperative blood loss in posterior lumbar interbody fusion

Junichi Kushioka, MD1, Tomoya Yamashita, MD2, Shinya Okuda, MD, PhD2, Takafumi Maeno, MD, PhD2, Tomiya Matsumoto, MD, PhD2, Ryoji Yamasaki, MD, PhD3, and Motoki Iwasaki, MD, PhD2 1Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine; 2Department of Orthopaedic Surgery, Osaka Rosai Hospital; and 3Department of Orthopaedic Surgery, Osaka Police Hospital, Osaka, Japan

Pages 363-367

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Multiple-hook fixation in revision spinal deformity surgery for patients with a previous multilevel fusion mass: technical note and preliminary outcomes

Ning Liu, MD1,3, and Kirkham B. Wood, MD1,2 1Department of Orthopaedic Surgery, Spine Service, Massachusetts General Hospital, Boston, Massachusetts; 2Department of Orthopaedic Surgery, Stanford University Medical Center, Redwood City, California; and 3Washington University in St. Louis, Brown School, St. Louis, Missouri

Pages 368-373

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Diagnostic accuracy of motor evoked potentials to detect neurological deficit during idiopathic scoliosis correction: a systematic review

Parthasarathy D. Thirumala, MD1,3, Donald J. Crammond, PhD1, Yoon K. Loke, MBBS4, Hannah L. Cheng1, Jessie Huang1, and Jeffrey R. Balzer, PhD1,2Departments of 1Neurological Surgery and 2Neuroscience, University of Pittsburgh; 3Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; and 4Norwich Medical School, University of East Anglia, Norwich, United Kingdom

Pages 374-383

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Spinal cord herniation repair with microstaples: case report

Pedro David Delgado-López, MD1, Cecilia Gil-Polo, MD, PhD1, Vicente Martín-Velasco, MD1, Javier Martín-Alonso, MD1, Ana María Galacho-Harriero, MD1, and Elena Araus-Galdós, MD2Departments of 1Neurosurgery and 2Neurophysiology, Hospital Universitario de Burgos, Spain

Pages 384-387

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Bone marrow stromal cell sheets may promote axonal regeneration and functional recovery with suppression of glial scar formation after spinal cord transection injury in rats

Akinori Okuda, MD1,2, Noriko Horii-Hayashi, PhD2, Takayo Sasagawa, MS2, Takamasa Shimizu, MD, PhD1, Hideki Shigematsu, MD, PhD1, Eiichiro Iwata, MD, PhD1, Yasuhiko Morimoto, MD1, Keisuke Masuda, MD1, Munehisa Koizumi, MD, PhD3, Manabu Akahane, MD, PhD4, Mayumi Nishi, MD, PhD2, and Yasuhito Tanaka, MD, PhD1 1Department of Orthopaedic Surgery, Nara Medical University, Kashihara; 2Department of Anatomy and Cell Biology, Faculty of Medicine, Nara Medical University, Kashihara; 3Spine and Spinal Cord Surgery Center, Nara Prefecture General Medical Center; and 4Department of Public Health, Health Management, and Policy, Nara Medical University, Kashihara, Nara, Japan

Pages 388-395

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Promotion of astrocytoma cell invasion by micro RNA–22 targeting of tissue inhibitor of matrix metalloproteinase–2

Yu-ichiro Ohnishi, MD, PhD1, Koichi Iwatsuki, MD, PhD1, Masahiro Ishihara, MD, PhD1, Toshika Ohkawa, MD, PhD2, Manabu Kinoshita, MD, PhD3, Koei Shinzawa, PhD4, Yasunori Fujimoto, MD, PhD1, and Toshiki Yoshimine, MD, PhD1Departments of 1Neurosurgery and 4Molecular Genetics, Osaka University Medical School; 2Department of Neurosurgery, Yao Municipal Hospital; and 3Department of Neurosurgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan

Pages 396-403

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Erratum: Screening via CT angiogram after traumatic cervical spine fractures: narrowing imaging to improve cost effectiveness. Experience of a Level I trauma center

Gabriel A. Smith, MDCase Western Reserve University School of Medicine, MetroHealth Medical Center, Cleveland, OH

Pages 404-404

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Letter to the Editor: Pedicle screw–based dynamic stabilization and adjacent-segment disease

Yu-Wen Cheng, MD1,2, Peng-Yuan Chang, MD1,2, Jau-Ching Wu, MD, PhD1,2, Chih-Chang Chang, MD1,2, Li-Yu Fay, MD1,2,3, Tsung-Hsi Tu, MD1,2,4, Wen-Cheng Huang, MD, PhD1,2, and Henrich Cheng, MD, PhD1,2,3 1Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan; 2School of Medicine, National Yang-Ming University, Taipei, Taiwan; 3Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan; and 4Molecular Medicine Program, Taiwan International Graduate Program, Academia Sinica, Taipei, Taiwan

Pages 405-406


Yu Han, MM, Jianguang Sun, MM, Shilei Huang, MM, and Guofu Pi, MM

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Letter to the Editor: Screening via CT angiogram and cervical spine fractures

Xiao Wu, BS, David Durand, MD, Vivek B. Kalra, MD, Sowmya Mahalingam, MD, and Ajay Malhotra, MD, MMMYale School of Medicine, New Haven, CT

Pages 406-407


Gabriel A. Smith, MD, Megan M. Lockwood, MD, and Michael P. Steinmetz, MD

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Letter to the Editor: Adult spinal deformity surgery: is it always worthwhile?

Enrico Tessitore, MD, and Oliver P. Gautschi, MDUniversity Hospital Geneva, Switzerland

Pages 408-409


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