a. Serve as a laboratory technician working under the supervision of a principal
investigator (Research/Clinical Scientist of same company) or contractor laboratory
manager/ supervisor (or same company) in performing laboratory procedure and
experiments as required for the phenotypic and genotypic characterization of MDRO.
b. Perform experimental work including serological assays, chemical assays, genetic and
molecular biology procedures, growth of solid and liquid cultures.
c. Perform routine laboratory duties required for the smooth and safe operation of
laboratory such as maintaining a supply of clean glassware, properly disposing of
hazardous biological and chemical waste, preparing reagents, and maintaining an
inventory of laboratory chemicals.
d. Maintain a laboratory notebook in which accurate and complete records of laboratory
work is maintained in accordance with accepted standards.
e. Follow laboratory SOP's and specific written experimental protocols as well as oral
instructions (same company) in performing assigned experimental work.
f. Submit reports and data summaries when applicable.
g. Comply with occupational health and safety standards and other applicable regulations
and guidelines which may include medical surveillance.
h. Attend relevant seminars, scientific conferences, and meetings to the MRSN.
i. Participate in the development of research protocols and grant proposals and in the
conduct of research related to MRSN activities.
j. Ensures quality specimens for laboratory testing.
k. Operate systems/methodologies in order to produce timely and accurate data for
patients, Quality Control (QC), and proficiency testing.
l. Report clinical data accurately and efficiently to ensure givers receive timely patient
information.
m. Works to improve and expand the skill set of others involved with this effort by
communicating and maintaining team knowledge (same company).
Associates Degree in a scientific or technical discipline, or the equivalent combination of education, professional training, or work experience.
CUSTOMER REQUIREMENT: Successful completion of a Medical Technologist program (BA or BS) or Medical
Laboratory Technician (AAS) program preferred
3-5 years of related scientific experience.
b. Demonstrates knowledge of operational and regulatory standards
c. Requires the capacity to serve as consultant and scientific advisor for MEDCOM
characterization of multi?]drug resistant bacteria. Work involves establishing, directing
basic and applied functional genomics to the MEDCOM Multi?]Drug Resistant Organism
Repository and Surveillance Network (MRSN).
d. Requires subject matter expertise and ability to provide scientific leadership in the
phenotypic and genotypic characterization of clinical isolates from within the Military
Healthcare System (MI?]IS).
e. Requires extensive experience and demonstrated capability in analyzing large datasets
to identify genomic features associated with microbial drug resistance, to determine
phylogenetic relationships among bacterial strains, and to perform epidemiological
analyses.
f. Involves scripting and programming for file management, parametric analyses, and postprocessing
data files.
g. Requires knowledge and experience writing scripts in languages such as Perl, in
environment shells such as bash, and common software packages for high content data
analysis such as R.
h. Requires experience processing microbial identification / antibiotic susceptibility testing
data generated on the three most widely used automated systems: Microscan, Phoenix
and Vitek2.
i. Requires expertise in genome sequence analysis and annotation. Experience analyzing
next?]generation sequence data and whole genome optical mapping data is essential, as
is familiarity with on?]line databases of bacterial genes, proteins and molecular
pathways.
j. Involves the development of complex data mining queries in coordination with
laboratory researchers and database administrators utilizing SQL.
k. Additional experience required in the following:
i. BACTERIOLOGY ?] VIRULENCE FACTORS
Work involves a comprehensive research program to discover the mechanism of
action of various bacterial virulence factors and their contributions to
pathogenesis. Direct a multidiscipline program that requires extensive current
knowledge of concepts in biochemistry, cell biology, microbiology and
immunology. Study the biosynthesis, structures and mechanism of action of
bacterial virulence factors (i.e. toxins, antigens. enzymes, at the molecular,
cellular and organismic level).
ii. MOLECULAR BIOLOGY?] GENOMICS
Work involves the funding and management of basic and applied research to
isolate, sequence, and analyze nucleic acid sequences derived from prokaryotic
pathogenic organisms. Require understanding of the principals and methods for
nucleic acid (RNA and DNA) isolation procedures from prokaryotic pathogens as
well as from a variety of eukaryotic host cells and tissues infected by these
pathogens. Work collaboratively with peers to establish direction and
supervision of work conducted by contractor technical and postdoctoral level
staff. Involve the production, isolation, and analysis of nucleic acids derived
from prokaryotic organisms and eukaryotic cells. Maintain a state?]of?]the?]art
prokaryotic sequencing and bioinformatics capability. Manage work conducted
under BioSafety Level 2 (BSL?]2) containment. Manage the establishment of a
completely electronic format of planning, collecting, and storage of laboratory
data. Establishes and conducts all operations under a Laboratory Information
Management System (LIMS). Report on progress, problems and corrective
actions. Assure compliance with normal laboratory operations including the
hazards and safeguards related to work involving infectious agents, toxic
chemicals, carcinogens, safe handling of animal as well as human tissues/fluids,
highly flammable materials and radiation hazards. Manage budget and overseas
the timely acquisition of laboratory equipment and supplies. Maintain
knowledge of and provide guidance to others in current and relevant scientific
literature. Prepare oral presentations, poster presentations and manuscripts
that communicate the scientific work being conducted.
iii. MOLECULAR GENETICS OF BACTERIAL DISEASES
Work involves pathogenesis and the genetics of pathogens and the interactions
of bacterial agents with the immune system to establish a technological base for
the assessment of militarily important pathogens. Execute research leading to
an increase in the defensive capability of identifying and treating novel
pathogens. Develop methods and appropriate research to establish a
technological base for the genetic analysis of pathogens of military importance
with an emphasis on determining the presence and nature of
extrachromosomal genetic elements.
As a trusted systems integrator for more than 50 years, General Dynamics Information Technology provides information technology (IT), systems engineering, professional services and simulation and training to customers in the defense, federal civilian government, health, homeland security, intelligence, state and local government and commercial sectors. With approximately 32,000 professionals worldwide, the company delivers IT enterprise solutions, manages large-scale, mission-critical IT programs and provides mission support services. GDIT is an Equal Opportunity/Affirmative Action Employer - Minorities/Females/Protected Veterans/Individuals with Disabilities.
*Location:* Silver Spring, MD
*Job ID Number:* 233666.1