**Johnson & Johnson companies are equal opportunity employers.**
SCIENTIST-7102140324
**Description**
Janssen Research & Development, L.L.C., a Johnson & Johnson Company is hiring a Scientist, Immunology to be located in Springhouse, PA.
Janssen Research & Development, L.L.C. develops treatments that improve the health and lifestyles of people worldwide. Research and development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, and reproductive medicine.
Janssen Pharmaceuticals, Inc., a pharmaceutical company of Johnson & Johnson, provides medicines for an array of health concerns in several therapeutic areas, including: attention deficit hyperactivity disorder (ADHD), cardiovascular disease, general medicine (acid reflux disease, infectious diseases), mental health (bipolar I disorder, schizophrenia), neurologics (Alzheimer’s disease, epilepsy, migraine prevention and treatment), pain management, and women’s health. Our ultimate goal is to help people live healthy lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market – from patients to practitioners, from clinics to hospitals. For more about Janssen Pharmaceuticals, Inc., one of the Pharmaceutical Companies of Johnson & Johnson, visit www.janssenpharmaceuticalsinc.com
The Scientist, Immunology will be a part of a drug discovery team focused on identification of novel targets and mechanisms underlying RA, IBD and Psoriasis. This role requires a deep understanding of the immune system, with a particular focus on mechanisms and pathways that regulate tolerance. Experience in in vitro and in vivo systems of autoimmune and inflammatory diseases is highly preferred. The Scientist is expected to work actively on the bench designing and executing experiments in support of various discovery immunology programs. The Scientist will be also expected to gain a significant understanding of the discovery strategy focused on RA, IBD and Psoriasis, and will work in close collaboration with colleagues within the Immunology therapeutic area to generate robust data packages to enable the discovery pipeline. Extensive familiarity with various cellular immunology assays and techniques including measures of T, B cell activation, innate cell activation, measuring of effector functions including cytokine production and intracellular signaling assays, phenotypic analysis using FACS etc. is absolutely required. The successful candidate is expected to be a critical member of the discovery team and will be responsible for formulating and executing innovative scientific approaches using state-of-the art technology. This role lends itself to very attractive future growth opportunities.
Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.
**Qualifications**
A PhD in Immunology with a minimum of 3 years of successful and productive post-graduate experience is required.
A deep understanding of the cellular immune components, and their role in autoimmune diseases and inflammation is required.
Demonstrated experience in independently designing and executing experiments focused on autoimmune diseases in context of T/B cell activation, effector function and/or regulation is highly preferred.
Experience with costimulatory and/or immuno-regulatory pathways is preferred.
Documented record of productivity as indicated by publications, presentations and/or patents is highly preferred.
Excellent communications skills are required as is a proven ability to work in a matrix collaborative environment is required.
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**Primary Location:**North America-United States-Pennsylvania-Spring House
**Organization:** Janssen Research & Development, LLC. (6084)
**Job Function:** Biology
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Johnson and Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, protected veteran status, or disability status, or any other characteristic protected by law.
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*Req ID:* 7102140324
*Date:* Thu, 27 03 2014 00:00:00 GMT
*Country:* US
*State:* PA
*City:* Spring House
*Postal Code:* 19477
*Locale:* en_US