The candidate will plan and lead laboratory experiments and assays associated with the development of novel cell culture media formulations and processes. The Staff Scientist works in a laboratory environment and is required to lift up to 40 lbs. As a Staff Scientist, you may be required to stand for long periods of time while performing duties. You must be able to work safely with chemicals and hazardous materials. A Staff Scientist must be able to work flexible hours. There are travel requirements of 5 10 %25.
Key Objectives of the role:
* Independently designs experimental plans, leads study execution, analyzes experimental data, generates laboratory protocols, and writes technical reports, quantitative analyses, and product summaries
* Works on complex and challenging problems of broad scope where analysis of situations or data requires a comprehensive evaluation of numerous factors within aggressive timelines
* Troubleshoots and solves difficult problems in the design/execution of development projects
* Exercises practical judgment within broadly defined practices and policies and exhibits creativity and foresight in selecting approaches and techniques for obtaining solutions
* Investigates, creates, and incorporates new methods and technologies to improve effectiveness of development workflows
* Actively capitalizes on knowledge of industry trends to identify new opportunities for novel product offerings that address customer pain points
* Maintains accurate lab notebook to support protection of intellectual property in accordance with relevant Thermo Fisher required standards
* Maintains high level of professional expertise and substantial knowledge of principles and theories through familiarity with competing technologies and/or products, review of current scientific literature, and attendance at scientific seminars and meetings
* Presents data at scientific conferences (external and internal) and prepares relevant publications
* Interacts closely with other internal departments (i.e., Marketing, Business Development, Quality, Operations and/or Technical Services) and with key thought leaders within the industry in the commercialization of new products
* Frequent technical interactions with outside collaborators through seminars and publications and with customers through teleconferences, site visits, and scientific meetings
* Complies with all company safety, training, and quality regulations (e.g., ISO compliance, GLP/GMP requirements, etc.) and procedures
* May be required to perform other related duties as required and/or assigned
Minimum Qualifications (must have):
* Bachelor s degree with 7 plus years of experience, Master's degree with 5 plus years of experience, or Ph.D. degree with 2 plus years of experience in Biology, Bioengineering, Biochemistry or other related discipline, or equivalent knowledge and experience
* Expertise in the methods and techniques of molecular biology and small-scale mammalian cell culture
* Experience with expression vector construction and cell line engineering
* Broad familiarity of scientific principles associated within bioprocessing
* Proven proficiency in data analysis, research design, troubleshooting, and the evaluation of new techniques and procedures for manufacturing reagents, systems, products or technologies
* Demonstrated ability to identify and solve difficult problems
* Excellent verbal and written communication skills and the ability to interpret and summarize scientific results in a clear, concise, & accurate manner
* Excellent organizational skills, including the ability to efficiently evaluate and adapt to changing project priorities
Preferred Qualifications (nice to have):
* Prior industrial experience, particularly in process development and/or cell culture media formulation development
* Proven proficiency in statistical design of experiments (DOE)
* Understanding of chemical, biochemical and physical interactions of cell culture media and reagent components
* Previous cell culture experience with cell lines used in protein production applications (e.g. CHO, HEK293, NS0)
* Previous experience with cell types used in cell therapy applications (e.g. T cells, MSC, ESC) or cell lines used in the production of viral vaccines (e.g. Vero, MRC-5, BHK)
* Familiarity with the operation of bench-top stirred tank bioreactors and related process development laboratory equipment as well as the scale-up of bioreactor and mixing systems
* Experience with high-throughput cell culture technologies (e.g. ambr15)
* Previous experience leading small technical teams
* Familiarity with project management techniques including tracking of project progress, resources and issues
Minimum Qualifications (must have)
Preferred Qualifications (nice to have)
EOE