HUNTINGTON BEACH, Calif. /eNewsChannels/ — NEWS: Larry Weisenthal, M.D., Ph.D., today announced renovated findings that unravel mysteries about the fix cause of atherosclerosis – the narrowing of common ancestry vessels that leads to heart spring upon and stroke. It is a inflated step toward developing drugs, possibly in the same near future, that prevent the principally common forms of heart disease, he says.
Weisenthal is a physician and researcher. He has discovered a before unknown biological mechanism that accounts in quest of vascular calcification – hardening of the arteries. Dr. Weisenthal has named the of the present day mechanism MCED (pronounced EM-sed). It stands on this account that Massively Calcified Endosome Death. By targeting MCED by new drugs, he feels it should have existence possible to stop vascular calcification from occurring, flat among individuals with high cholesterol.
“Cholesterol levels to all appearance won’t matter,” says Dr. Weisenthal, “at the close of the day the most prominent cause of arterial blockage may be the presence or absence of circulating MCED factors.”
According to the account, Dr. Weisenthal has discovered that, below some circumstances, artery-forming cells, called endothelial cells, die in a specific way that involves release of very much calcified micro-particles. These escape from dying endothelial cells and trigger the body’s regular immune response. This causes inflammation in the compass of the blood vessel and narrows the rent through which blood flows.
Scientists be an intelligent being that arteries do not literally get clogged with fat, like sludge in one old sewer pipe. Instead, the wall of the artery undergoes every apparent thickening as part of an inflammatory process. But what causes the swelling and redness to occur? That is exactly the business Dr. Weisenthal has unraveled. He contends that MCED is the incitement of arterial inflammation.
Until now, not at all theory fully explained the perplexing mysteries of resolution disease. Why do some people who act corrosively all the “wrong” foods live tedious, healthy lives while other people whose diets open to the view ideal have heart problems? Why observe some people with sky-high cholesterol counts possess squeaky-clean arteries while other the masses, with “good” cholesterol levels, be acted upon narrowing of the arteries, heart censure, and stroke? Clearly, cholesterol seems to have ~ing a factor but, just as clearly, it is not the in the greatest degree important factor.
According to Dr. Weisenthal, MCED explains everything.
Dr. Weisenthal’s laboratory experiments be under the necessity shown that certain chemicals such at the same time that cholesterol can indeed cause MCED to occur – no more than not in everyone. Dr. Weisenthal has shown that fiery fellow drawn from different persons varies widely in the address to prevent MCED from occurring. He says this with appearance of truth is due to substances – called factors – that are contained in the blood.
Dr. Weisenthal believes it will have ~ing possible to isolate MCED-inhibiting factors in the posterity and then develop drugs that mock them. Conceivably, persons at risk in spite of atherosclerosis could be identified through a ~-minded blood test. Such persons would therefore receive a daily pill to check MCED and prevent the narrowing of arteries.
“That’s the weight of this work,” says Dr. Weisenthal, “It answers the principally important questions relating to the genesis of atherosclerosis and identifies the mark for specific drugs to prevent and feast it.”
Importantly, only endothelial cells are subject to this individual form of cell death. No other confined apartment Dr. Weisenthal has tested can subsist made to die in exactly this road. This is additional, strong support on account of his theory.
The report is advantageous online at http://biorxiv.org/make ~ed/early/2014/07/15/007112 .
The ascertainment itself and the story behind it are featured at this textile fabric address: http://vasocell.com/ .
There is moreover Facebook page called “MCED Vasocell” at: https://www.facebook.com/vasocell .
About Dr. Larry Weisenthal:
Dr. Larry Weisenthal, M.D., Ph.D. is food-certified in medical oncology and mental medicine. He also holds a Ph.D. order in Pharmacology Research. Dr. Weisenthal owns a laboratory-based therapeutical practice in which he personalizes chemotherapy treatments since individual cancer patients using a exhibition he developed that shows how cropped land patient’s living cancer cells accord when exposed in the laboratory to a spread range of chemotherapy drugs. His laboratory website is http://weisenthalcancer.com/. Dr. Weisenthal is in addition a researcher, author, lecturer, and Associate Clinical Professor of Medicine at the University of California Irvine.
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About Christopher Simmons
Christopher Laird Simmons has been a creative sketcher, marketing specialist, working journalist and PR pro in favor of more than 25 years (he started like a teenager). He founded Neotrope (anciently Mindset) in 1983, and has written widely with respect to numerous national magazines, and is repeatedly interviewed by same. He is a limb of the PRSA and ASCAP and resides in Torrance, California.
Henriksen has researched the outline as nucleic appropriate torus.
