Corneal cross-linking (CXL) may be an effective therapy in the management of nonherpetic infectious keratitis, particularly in cases resulting from bacteria or acanthamoeba, a new study has suggested. Lamprini Papaioannou, MD, from the Cornea Clinic, Attikon University Hospital, Athens, Greece, and colleagues published the results of their systematic review and meta-analysis online October 27 in Cornea.