Ludwik Leibler and his colleagues reported spectacular evidence that nanoparticle aqueous solutions - a method invented a few months ago at ESPCI ParisTech - do indeed heal wounds in vivo.
Wound healing using a nanoparticle aqueous solution (left) vs. stitching (right) ©ESPCI
See the movie.
These results have just been published in Angewandte Chemie:
Organ Repair, Hemostasis, and In Vivo Bonding of Medical Devices by Aqueous Solutions of Nanoparticles
Anne Meddahi-Pellé, Aurélie Legrand, Alba Marcellan, Liliane Louedec, Didier Letourneur and Ludwik Leibler
Angewandte Chemie, International Edition published online April 16, 2014
DOI: 10.1002/anie.201401043
Read the joint Press Release from CNRS/ESPCI/INSERM/Paris Diderot/Paris 13.
The work was performed by a team of scientists from ESPCI ParisTech, CNRS, INSERM, Université Paris Diderot, Université Paris 13 and Université Pierre-et-Marie-Curie (UPMC), at the Soft Matter and Chemistry Laboratory (UMR CNRS/ESPCI ParisTech) and the Laboratory for Vascular Translational Science (LVTS - INSERM/Université Paris Diderot/Université Paris 13).
Science
Ludwik Leibler
ludwik.leibler@espci.fr
01 40 79 51 25
Press
Sylvain Gilat
sylvain.gilat@espci.fr
01 40 79 58 76
Exploring Further
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The joint Press Release from CNRS/ESPCI/INSERM/Paris Diderot/Paris 13.
The seminal article published in Nature in December 2013:
Nanoparticle solutions as adhesives for gels and biological tissues
Séverine Rose, Alexandre Prevoteau, Paul Elzière, Dominique Hourdet, Alba Marcellan & Ludwik Leibler
doi:10.1038/nature12806
The corresponding press release: Revolutionary method for gluing gels and biological tissues
Media coverage
Des chercheurs inventent une nouvelle façon de réparer les organes (Le Journal de la Science)
Une "nano-colle" pour réparer les organes et refermer les plaies (Sciences & Avenir)
Une nano colle pour réparer les organes et refermer les plaies (blog François Gros)
Une stratégie simple et inédite pour réparer des organes (Techno-science.net)
Chirurgie adhésive et nano point de suture (RFI)
Des nanoparticules pour coller des plaies et réparer des organes (Pourquoi Docteur)
Une colle de nanoparticules pour réparer des organes (Top Santé)
Une nano-colle bientôt disponible dans les blocs opératoires (bluewin.ch)
Une nouvelle "colle" chirurgicale à l'étude (Le Point)
Suture: Une colle chirurgicale à base de nanoparticules (Santé Log)
Cicatrisation : la fin des points de suture ? (Doctissimo)
‘Nanoglue' headed for hospital operating rooms (The Malaysian Insider)
New technique to glue shut incisions and repair wounded organs (Democratic Underground)
Adhesion method could revolutionize surgical practice and regenerative medicine (Medical News Today)
Nanoparticles replace needle and thread for wound closure (NanoWerk)
High-performing surgical adhesive utilizes nanoparticles (freenewspos.com, gizmag.com)
Adhesive Gel Facilitates Organ Repair (Medical Design Technology Magazine)
French researchers introduce new method to effectively control bleeding and repair tissues (News Medical)
Look, ma, no stitches: 'Nanoglue' shuts wounds in seconds (The Star Online)
Nanoparticle solution closes deep wounds in 30 seconds (Medical Technology Business Europe)
Healing : slutten av masker ? (no.france-sante.org)
創新策略使器官修補更便利 (Only Perception blog)
Nanoparticles close wounds (The Loudest Geeks blog)
Nanoparticles Replace Needle and Thread (Chemistry Views)