Public Health Genomics Knowledge Base (v1.0)
Incidental findings
Last Updated: May 26, 2016
DECIDE: a Decision Support Tool to Facilitate Parents' Choices Regarding Genome-Wide Sequencing.
Birch Patricia et al. Journal of genetic counseling 2016 May
Ethical considerations in biobanks: how a public health ethics perspective sheds new light on old controversies.
Virani Alice Hawkins et al. Journal of genetic counseling 2015 Jun 24(3) 428-32
The challenge of consent in clinical genome-wide testing.
Burke Katherine et al. Archives of disease in childhood 2016 Apr
Research participant interest in primary, secondary, and incidental genomic findings.
Loud Jennifer T et al. Genetics in medicine : official journal of the American College of Medical Genetics 2016 Apr
Patient preferences regarding incidental genomic findings discovered during tumor profiling.
Yushak Melinda L et al. Cancer 2016 Mar
Ethical Considerations for the Return of Incidental Findings in Ophthalmic Genomic Research.
Souzeau Emmanuelle et al. Translational vision science & technology 2016 Feb 5(1) 3
Patients' views on incidental findings from clinical exome sequencing.
Clift Kristin E et al. Applied & translational genomics 2015 Mar 438-43
Incidental Findings: The Importance of Pretest Counseling.
Buchtel Kathryn M et al. Pediatric neurology briefs 2015 Dec 29(12) 91
A Clinical Service to Support the Return of Secondary Genomic Findings in Human Research
AJ Darnell et al, AM J Human Genetics, March 3, 2016
Incidental findings of uncertain significance: To know or not to know - that is not the question.
Hofmann Bjørn et al. BMC medical ethics 2016 (1) 13
Generating a taxonomy for genetic conditions relevant to reproductive planning.
Korngiebel Diane M et al. American journal of medical genetics. Part A 2016 Mar 170(3) 565-73
Oncologists' and cancer patients' views on whole-exome sequencing and incidental findings: results from the CanSeq study.
Gray Stacy W et al. Genetics in medicine : official journal of the American College of Medical Genetics 2016 Feb
Improving performance of multigene panels for genomic analysis of cancer predisposition.
Shirts Brian H et al. Genetics in medicine : official journal of the American College of Medical Genetics 2016 Feb
Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records.
Van Driest Sara L et al. JAMA 2016 Jan 315(1) 47-57
In Guanine We Trust: Genetic Testing and the Sense of Coherence.
DuBois James M et al. Narrative inquiry in bioethics 2015 5(3) 237-44
Automatic Placement of Genomic Research Results in Medical Records: Do Researchers Have a Duty? Should Participants Have a Choice?
Prince Anya E R et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec 43(4) 827-42
You have a possibly faulty gene. Should your doctor tell you?
By Patrick Skerrett, STAT, January 5, 2016
Next-generation sequencing using a pre-designed gene panel for the molecular diagnosis of congenital disorders in pediatric patients.
Lim Eileen C P et al. Human genomics 2015 9(1) 33
Statement of principles on the return of research results and incidental findings in paediatric research: a multi-site consultative process.
Published on 2015 by The Network of Applied Genetic Medicine
Incidental Findings with Genomic Testing: Implications for Genetic Counseling Practice.
Roche Myra I et al. Current genetic medicine reports 3(4) 166-176
Precision medicine ethics: selected issues and developments in next-generation sequencing, clinical oncology, and ethics.
Fiore Robin N et al. Current opinion in oncology 2015 Nov
Review of Commercially Available Epilepsy Genetic Panels.
Chambers Chelsea et al. Journal of genetic counseling 2015 Nov
To disclose, or not to disclose? Context matters.
Rahimzadeh Vasiliki et al. European journal of human genetics : EJHG 2015 Mar 23(3) 279-84
Genetics: Fluent in DNA.
Eisenstein Michael et al. Nature 2015 Oct 526(7571) 151-2
Returning a Research Participant's Genomic Results to Relatives: Analysis and Recommendations.
Published on 2015 by Expert panel
Molecular analysis of clinical isolates previously diagnosed as Mycobacterium intracellulare reveals incidental findings of "Mycobacterium indicus pranii" genotypes in human lung infection.
Kim Su-Young, Park Hye Yun, Jeong Byeong-Ho, Jeon Kyeongman, Huh Hee Jae, Ki Chang-Seok, Lee Nam Yong, Han Seung-Jung, Shin Sung Jae, Koh Won-Jung.BMC infectious diseases 2015 (1) 406
Minimum information for reporting next generation sequence genotyping (MIRING): Guidelines for reporting HLA and KIR genotyping via next generation sequencing.
Mack Steven J et al. Human immunology 2015 Sep
Attitudes of the general public towards the disclosure of individual research results and incidental findings from biobank genomic research in Australia.
Fleming J et al. Intern Med J 2015 Sep 21.
A protocol for the identification and validation of novel genetic causes of kidney disease.
Mallett Andrew, et al. BMC nephrology 2015 0 (1) 152
The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position Statement of the Canadian College of Medical Geneticists.
Published on 2015 by Canadian College of Medical Geneticists
CDC Information (1)
CDC-Authored Pub (2)
Human (12)
Pathogen (0)
Human (42)
Pathogen (1)
Guidelines (6)
Tier Table (0)
Synthesis (7)
Relevant Resources
Cancer Genomics and Epidemiology Navigator (CGEN)
Genetics and Genomics Competencies Center (G2C2)
NIH Genetic Testing Registry
NIH MedGen Database
Online Mendelian Inheritance in Man (OMIM)
PharmGKB