Manforce Staylong Gel is an allopathic cream / gel for external use,
manufactured by Mankind Pharma. This gel is used in preventing Premature
ejaculation PE / early (EE) / rapid ejaculation (RE), the common male sexual
dysfunction.
Premature Ejaculation involves
1. Short ejaculatory latency: ejaculation always or nearly always occurs
prior to or within about 1 minute of vaginal penetration
2. Lack of control over ejaculation: inability to delay ejaculation on all or
nearly all vaginal penetrations.
3. Lack of sexual satisfaction: poor sexual performance leading to distress,
frustration and/or the avoidance of sexual encounters
The ingredients of gel belong to the amide class of local anesthetics.
Lidocaine and prilocaine block sodium ion channels required for the initiation
and conduction of neuronal impulses, resulting in local anesthesia to the glans
penis mucosal surface and thus preventing primary premature ejaculation in adult
men.
Here is given more about this medicine, such as benefits,
indication/therapeutic uses, composition and dosage.
Brand: Mankind Pharma
Category: Cream / gel
For: Premature ejaculation (PE)
Dosage Form / Route: Cream / topical
Availability as: 1 gm Sachet and 10 gm Tube
Price / MRP: Rs. 19.45 for 1 gram sachet and Rs. 126.00 for 10 gm
Tube
Composition of Manforce Staylong Gel
Active substance: lidocaine and prilocaine gel (Anaesthetics, local)
The chemical name of lidocaine is 2-(diethylamino)-N-(2, 6-dimethylphenyl)
acetamide. It is a white or almost white, crystalline powder, practically
insoluble in water and very soluble in alcohol and in methylene chloride.
The chemical name of prilocaine is
N-(2-methylphenyl)-2-propylamino-propanamide. Prilocaine is a white or almost
white, crystalline powder, slightly soluble in water and very soluble in acetone
and in ethanol.
Lidocaine has a rapid onset of action and anaesthesia is obtained within a
few minutes, with an intermediate duration of action. Prilocaine has a slower
onset of action with slightly longer duration of action.
The combination of lidocaine and prilocaine provides a rapid onset of
action, optimized penetration, maximum depth of neural blockade and lesser time
of onset of numbness. The gel also contains other ingredients and purified
water.
Important Therapeutic Uses of Manforce Staylong Gel
Manforce Staylong Gel is indicated for the treatment of primary premature
ejaculation in adult men.
What is premature ejaculation (PE)?
Premature ejaculation (PE) is most common male sexual disorder. It is
inability to control or delay ejaculation, and thus affecting both partners.
PE is the occurrence of ejaculation before or very soon after the beginning
of intercourse (occurs prior to or within about one minute of vaginal
penetration). It is persistent or recurrent condition and occur after minimal
sexual stimulation. The person ejaculates before, on, or shortly after
penetration and before the person wishes it. The patient has little or no
voluntary control.
Though it does not involve any impairment of fertility, when intravaginal
ejaculation occurs but causes poor sexual performance, distress, bother,
frustration and/or the avoidance of sexual intimacy.
How to Use Manforce Staylong Gel
The gel should be applied before sexual intercourse.
Apply the gel for 20 minutes on penis.
Apply thinly to the glans penis and distal shaft and covered by a condom for
20-25 minutes. If the condom is removed for intercourse, residual cream should
be washed off.
The use of condom is required to minimize the effect of the cream upon
vaginal sensation, as it may cause lower sensation.
The high water content of this mixture enables it to penetrate the intact
skin of the penis.
20 min of application time before sexual contact is the optimum period. It
will increase the time before ejaculation by 6-8 minutes.
If you apply more than 30 minutes there are chances of erection loss because
of numbness.
Side effects
The most common side effects are hypoaesthesia (reduced sensation) and
genital burning in both men and women, plus erectile dysfunction in men and
headache, influenza, naso-pharyngitis and vulvovaginal discomfort in female
sexual partners.
There is reduced feeling in and around the penis.
There is lesser feeling in and around vagina on contact.
It may reduce sperm motility.
Use with Caution in patients with Anaemia, congenital or acquired
methaemoglobinaemia or patients on concomitant therapy.
A higher rate of erectile dysfunction and male genital hypoaesthesia may be
experienced when using it with male condoms.
Care should be taken not to allow gel to come in contact with the eye, as it
may cause eye irritation. Also the loss of protective reflexes can permit
corneal irritation and potential abrasion.
If contact with the eye occurs, immediately rinse the eye with cold water or
saline solution and cover them gently until any effects, such as numbness, wear
off.
When contacted with female genitalia or anal lining, it could be absorbed
and temporary local numbness/anesthesia is likely to result. This hypoaesthesia
may mask normal pain sensations and, therefore, increase the dangers of
localized injury as it reduce the ability to feel pain.
Do not use if
If you or your sexual partner are allergic to lidocaine or prilocaine or any
of the other ingredients of this medicine.
If you or your sexual partner have a history of allergy or sensitivity to
other local anaesthetics with a similar structure (known as amide-type local
anaesthetics).
Patients hoping to achieve conception should either avoid using this Gel,
or, if it is essential to achieve penetration, should wash the glans penis as
thoroughly as possible prior to intercourse. It may reduce the possibility of
pregnancy.
Excessive uses can cause
Symptoms of using too much Gel are listed below:
Feeling light-headed or dizzy
Tingling of the skin around the mouth and
Numbness of the tongue
Abnormal taste
Blurred vision
Ringing in the ears
There is also a risk of a disorder reducing the amount of oxygen in the
blood (methaemoglobinaemia). This is more likely when certain medicines have
been taken at the same time.
In serious cases of overdose, symptoms may include fits, low blood pressure,
slowed breathing, stopped breathing and altered heartbeat. These effects may be
life-threatening.